The Report

Accelerating Deep Tech in Latin America

Opportunities, Challenges & Recommendations

120 pages · LADP

Accelerating Deep Tech in Latin America
Accelerating Deep Tech in Latin America
01 / 29 4 min

Foreword

Leonardo Quattrucci & Marcus Alburez · Co-founders of the LADP

p. 5

Geopolitics is re-shaping the geography of innovation. In 2025, countries compete for technological superiority, splitting the world back into spheres of influence. In a way, the 2020s are the new 1970s. Nations have restored Cold War aims: to outcompete rivals by appropriating the resources necessary to develop critical technologies with strategic autonomy.

There are, however, significant differences between now and the Cold War era. First, the portfolio of technologies considered critical to national interests is broader and deeper, ranging from advanced artificial intelligence to quantum technologies and biotechnologies.

Second, the supply chain necessary to construct these technologies is inherently global. Protectionist strategies to re-shore production clash against the networked nature of innovation. Today, "no country alone can make an iPhone", as economist Eric Beinhocker put it. Deep Tech presents even greater barriers to autonomous development, given the complexity and distribution of inputs it requires, from rare minerals to skilled labor.

Finally, with traditional alliances fading, the global race for competitiveness is contested by more players with their own interests. Today’s world has more than two poles of influence. These new geometries of power leave room for new players to affirm themselves on the global stage. Latin America is one such player.

Latin America has the resources to move from a battleground for technological appropriation to a strategic actor in tech-driven geopolitics.

Latin America has traditionally had a passive role in the development of the global technology industry. It has traded at a deficit with bigger partners, serving skills, resources, and market opportunities at a discount, an effect widely known as the "Latin American Discount." It is a function of the institutional fragility of individual countries in the region and of the region’s fragmentation, which prevents it from leveraging its size and competitive advantages as a bloc. Foreign investors cannot value opportunities at their actual worth when the context is plagued by uncertain rules, frequent corruption, and inadequate public-sector de-risking of emerging markets.

Yet current changes in geopolitics can shift the position of Latin America from a Deep Tech vassal to a stronghold. This is the thesis behind the Latin American Dynamism Project: to accelerate the development and investment of frontier technologies in Latin America. The region is home to 42% of the world’s biodiversity; controls the lithium triangle, which contains 58% of global reserves; possesses abundant clean-energy potential, critical for scaling compute-intensive industries; and benefits from a booming nearshoring trend. With a GDP of roughly USD 6 trillion, almost double that of India but with barely half the population, the region combines large-market scale with significant availability for greenfield development.

What Latin America lacks is the network effects, in infrastructure, capital, and human talent, that can catalyse its potential into strategic autonomy, founded upon technological competitiveness. Realizing this potential will require coordinated action across the region: no single country has the scale, resources, and institutional reach to compete alone in the global Deep Tech race. The LADP addresses this gap by providing unprecedented insights to public and private decision-makers.

This report shows regional and global decision-makers a path to making LATAM an autonomous and reputable player in the global race for technological competitiveness.

This inaugural LADP report reveals more than a set of surprising data, which shows that LATAM is already a theatre for overlooked inventions. It shows regional and global decision-makers a path to making LATAM an autonomous and reputable player in the global race for technological competitiveness. Some countries, such as China, have long understood this, undertaking for a decade now policies of appropriation of natural resources. Others, from Latin American countries to traditional Western allies, have been slower to realise the potential of the region as more than the sum of its parts.

We publish these insights with the ambition to catalyze conversations, communities, and ecosystems that accelerate the transition of Latin America from a battleground for technological appropriation to a strategic actor in tech-driven geopolitics.

# Acknowledgments

This report was authored by Claudio Cifuentes Lobo, Marcus Alburez, Leonardo Quattrucci, Verónica Jijón and Said Saillant, with Nick Cohen and Fausto Carbajal Glass providing essential editorial guidance. Their combined expertise in data analysis, regional policy, and ecosystem development underpins every section of this publication. Production, design, data science, and communications were handled by Lucía Fenoglio, Solange Rodríguez, Milene Broche, Sebastián Díaz, Agustina Sojit, and Marco Tebélan.

To shape our findings, we spoke with almost 100 contributors and partnered with 17 organizations, venture-capital executives, policy-makers and ecosystem leaders, who generously shared their time and candid perspectives. This report was made possible by a grant from the International Strategy Forum, founded by Dr. Eric Schmidt, former CEO and Chairman of Google.

02 / 29 1 min

Executive Summary

Why LATAM is primed for Deep Tech

p. 8

Latin America pairs the inputs for frontier science with a market that has chronically underpriced them. The problems and the opportunities are two sides of the same coin. The report combines a database of 2,566 deep tech ventures with more than 100 interviews and five roundtables to map the ecosystem and to chart a path from the "LATAM Discount" to fair value.

# The problems

$15 Per-capita deep tech investment, half of Europe’s, and roughly a tenth of the United States’
~60% Of R&D in LATAM is government-funded, roughly the inverse of advanced economies
–51% MSCI LATAM valuation discount vs. the world, far above the –13.9% historical average
72% Of ventures remain at Seed; only 19% advance to Series A

# The opportunities

865k STEM researchers, but under 1% work in deep tech: a 100× runway of untapped talent
72% Gross average return on LATAM biotech startups, 2015–2023 (SOSV/IndieBio)
219% YoY deep tech funding growth in 2024, the fastest-growing sector
20× Projected deep tech ecosystem growth by 2032 (IDB)

The report groups its 20 recommendations into three arcs: what companies must do to become investable (Market Readiness), what unlocks investor confidence (Investor Readiness), and the regional coalition that ties it together, plus five further-research initiatives. The through-line is that the discount is a temporary mispricing driven by solvable structural factors, not permanently inferior fundamentals.

Explore all 20 recommendations Filter the full playbook by theme and audience.
03 / 29 2 min

Methodology

p. 13

This report combines quantitative and qualitative research methods to provide a comprehensive overview of the Deep Tech ecosystem in Latin America.

# Quantitative approach

We began with a dataset of 5,000 Deep Tech companies from LATAM, sourced primarily from Tracxn. After a review process, we retained ~2,500 companies for our final analysis. The data cutoff date was March 2025. To assist with accuracy in classification, we employed large language models (LLMs) for initial categorization, supplemented by meticulous manual validation.

For the manual checks, our team reviewed open-source materials, including patents, scientific publications, documentation, and corporate disclosures, to verify whether companies met established criteria for Deep Tech classification. The primary challenge involved distinguishing companies that leverage trendy technologies like Artificial Intelligence primarily as superficial marketing strategies from those genuinely developing novel, scientifically rigorous solutions.

Another critical obstacle was the lack of a shared, comprehensive, and openly accessible regional database. During our literature review, we found that existing reports frequently rely on proprietary datasets or private data brokers, limiting their value as a universally acceptable benchmark for ecosystem mapping. It is important to note that this is not an exhaustive database, but the most complete mapping we have seen to date.

To classify the companies by Deep Tech vertical, we took the 12 categories proposed by the 2023 Deep Tech: The New Wave report, backed by the Inter-American Development Bank: Robotics, Spacetech, Advanced Mobility, Biotechnology, Blockchain, Artificial Intelligence, Cleantech, Advanced Materials, Healthtech, Infinite Computing, Advanced Manufacturing, and Nanotechnology. To classify the companies by industry, we took the 8 categories proposed by EMERGE’s 2024 Relatório Deep Tech Brasil: Agribusiness & Animal Health, Food & Beverages, Cosmetics & Wellness, Energy, Chemicals, Petrochemicals & Materials, Human Health & Pharmaceuticals, Sustainability & Environment, and Other.

# Qualitative approach

Our qualitative research consisted of 5 roundtables and 100+ interviews with stakeholders across the ecosystem, including founders, investors, accelerators, researchers, and government actors. We asked them: what key gaps make LATAM investment less attractive to global VCs, and which resources would help bridge that gap? What do investors in LATAM’s Deep Tech ecosystem look for when deciding to fund startups at both the regional and global levels? How would you design a regional coalition that bridges local startups with global investment?

This report synthesizes insights from these conversations without attributing specific comments. We applied an obstacles-first lens to surface the binding constraints blocking ecosystem transformation, grounding our recommendations in removing root causes rather than proposing generic, solution-first fixes.

~2,566 ventures in the final database (data cutoff March 2025)
100+ interviews & 5 roundtables
17 partner organizations
12 deep tech verticals (IDB taxonomy)
04 / 29 5 min

What is Deep Tech?

p. 14

At its core, Deep Tech is the business of turning frontier science into products, the commercialisation of laboratory breakthroughs through structured technology-transfer processes. Whether the advance comes from a new material, a novel bioprocess, or a cutting-edge AI algorithm, the venture’s value proposition hinges on owning (or licensing) that underlying intellectual property and engineering it into a scalable solution that can redefine an industry.

# Five hallmarks

These technologies share five hallmarks, as noted in previous literature:

  1. Radical novelty, they introduce genuinely new technical capabilities.
  2. Fast growth, research, patents and investment expand rapidly.
  3. Coherence, a recognizable knowledge base and community forms around them.
  4. High-impact potential, often with long development timelines, their main socioeconomic effects are expected, not fully realised.
  5. Uncertainty & ambiguity, outcomes, markets and standards are still fluid.

By contrast, sectors such as fintech or general consumer software build mainly on technologies that already exist. They remix mature stacks of code and cloud infrastructure to create new user experiences or business models, but do not introduce a fundamentally new technology layer. In that sense they are sometimes dubbed "shallow tech" or "regular tech", innovations driven more by application design than by scientific discovery.

In Latin America, Deep Tech ventures are commonly labelled Emprendimientos de Base Científico-Tecnológica (EBCT) amongst policy papers, innovation-law frameworks and regional multilaterals like ECLAC. In China, we have found that the homologous term is "New Infrastructure," embedded in State Council guidelines and provincial five-year plans as the umbrella for AI, advanced manufacturing, and other Deep Tech priorities.

Seven common Deep Tech categories: definitions and example use cases
CategoryDefinitionExample use caseValue of the use case
Artificial IntelligenceThe ability of a machine or computer system to perform cognitive functions usually associated with humans, such as learning, problem-solving, and decision-making.In healthcare, improving diagnosis accuracy with medical-imaging devices (e.g. Samsung’s ultrasound-based tool, which raised breast-lesion diagnosis accuracy by ~5%).Enhances the customer relationship, better deals, virtual product trials, subscription management, payment verification, done in a privacy-friendly way.
Advanced MaterialsTechnology that modifies or engineers materials at a molecular level to create superior properties: enhanced durability, conductivity, or sustainability.Environmentally friendly batteries for electric vehicles (e.g. Tesla, General Motors), storing and releasing energy more efficiently.Supports climate and eco-friendly transformations; foundational to renewable energy systems and lightweight structures.
BiotechnologyThe use of living organisms or biological systems to create products, technologies, or processes that benefit humanity in health, agriculture, and energy.Liquid biofuels and methane from organic waste (e.g. ENI, ExxonMobil), using microorganisms to transform waste into energy.Improves sustainability; addresses global health through new medicines and food scarcity through enhanced agricultural products.
BlockchainA decentralized, immutable ledger technology that stores transactions and tracks assets, enabling secure, transparent records without a central authority.Tracking loan conditions between borrowers and lenders end-to-end (e.g. Indra borrowing €75 million from BBVA).Enhances tracking, traceability and safety in distribution; greater transparency in negotiations and supply chains.
Robotics and DronesThe use of machines to perform automated tasks, often in complex or hazardous environments; includes flying craft and remote-controlled systems.Automated store systems retrieving products from shelves (e.g. Amazon Robotics); drones for item pre-sequencing or last-mile delivery.Speeds up traditional processes such as pallet movement and barcode scans; improves order accuracy and shortens wait times.
Photonics and ElectronicsTechnology that enhances the properties of photons (light) to transmit information or actuate; a similar process with electrons in electronic devices.Advanced cameras, thermal or multi-spectral sensors for food safety (e.g. PepsiCo’s vision-inspection systems detecting potato defects).Increases transparency and customer trust; critical for telecommunications, computing, and medical diagnostics.
Quantum ComputingAnother way of processing information, leveraging the properties of matter at a nanoscale to perform calculations impossible for classical computers.Optimizing radio cells in telecommunications (e.g. operator TIM, using quantum principles with hardware maker D-Wave).Reliable, high-performance mobile services; potential to solve complex problems in medicine, finance, and materials science.

Source: IESE, How Corporate Giants Can Better Collaborate with Deep-Tech Start-ups

# Deep Tech investment: demystifying the risk

Beyond defining Deep Tech itself, the primary hesitation surrounding investment often emerges from evaluating critical metrics, particularly funding cycles and return on investment, in comparison to traditional technology sectors such as fintech, where conventional tech typically demonstrates immediate and steady growth upon receiving capital. This concern can be especially pronounced in LATAM, where investors are familiar with shorter business cycles and may be reluctant to wait several years for tangible returns.

Fortunately, various studies have started to quantify these concerns. A McKinsey report analyzing European and U.S. Deep Tech funds reveals an average net internal rate of return (IRR) of 17%, outperforming traditional tech funds, which yield an average of 10%. However, the absence of directly comparable LATAM data complicates contextualizing these findings, underscoring the need for localized research. The 2025 European Deep Tech Report identified and addressed eight prevalent misconceptions about Deep Tech investments.

Common (mis)conceptions about Deep Tech
QuestionVerdictDetail
Is Deep Tech an undefined term?NoDeep Tech is novel science being shipped in a first-of-a-kind product.
Is Deep Tech a new phenomenon in venture capital?NoDeep Tech venture financing has always existed and shaped the sovereignty of nations.
Do Deep Tech companies need more capital?YesBut often money is spent on building moats.
Do Deep Tech companies take longer to achieve revenue?Yes & noTrue in the early years, false at later stages.
Do Deep Tech companies fail more often?NoSimilar failure rates compared to regular tech.
Do Deep Tech companies need more time to exit?NoSimilar exit timelines compared to regular tech.
Do Deep Tech companies have larger exits?InconclusiveSome large outcomes exist; Europe needs more big exits.
Does Deep Tech investing deliver top returns?YesSome data shows higher IRRs than regular tech.

Source: Hello Tomorrow, The 2025 European Deep Tech Report

While precise metrics for Latin America’s Deep Tech ecosystem, and granular KPIs for each vertical, are still under development, a high-level risk-profile comparison helps illustrate the fundamental differences. Deep Tech startups carry substantially higher technology risk, require large upfront capital, and face protracted development cycles measured in years rather than months. Yet, once past those hurdles, they enjoy a powerful competitive moat, anchored in proprietary scientific breakthroughs, extensive IP portfolios, and teams of niche technical experts, that most "regular" tech firms simply cannot replicate.

05 / 29 3 min

Structural Challenges & Technological Opportunities

p. 20

Latin America sits at a pivotal crossroads. On one flank, a web of long-standing deficits, in healthcare, learning, public trust, labor formality, financial inclusion, infrastructure, energy, and cybersecurity, continues to sap productivity and widen inequality.

Roughly 140 million people still lack reliable access to basic health services, and the latest PISA results reveal that teenagers in the region perform the equivalent of three to seven school-years behind their OECD peers in mathematics. Confidence in government has slipped so far that seven in ten citizens express little or no trust in their national institutions, fuelling political volatility just as the digital economy demands stable rules of the game. Add a labor market in which nearly one-half of jobs are informal, a persistent digital divide that leaves 230 million Latin Americans offline, and rising cyber-incidents, LATAM became the world’s fastest-growing region for disclosed cyber-incidents by 2024, and Deep Tech innovation can seem a distant luxury.

Yet the very scale of these gaps hints at outsized opportunity.

The region commands world-class biodiversity, booming renewable-energy corridors, and a growing cadre of STEM researchers eager to found science-based companies. This potential is most evident in lithium, where Latin America holds nearly two thirds of global reserves, concentrated in the "Lithium Triangle" of Bolivia (24%), Argentina (22%) and Chile (11%), though Chile has led the way by turning its reserves into commercial production.

Why the region is primed
42%Biodiversity
58%Lithium resources
65%Renewable electricity
865kSTEM researchers

The raw inputs for frontier science are abundant: biodiversity, lithium, clean power and a deep pool of researchers.

As originally publishedAs of 2025Report p.23

The figure as the report published it, September 2025.

SourcesLatin American Dynamism Project (LADP), Accelerating Deep Tech in Latin America; Inter-American Development Bank (IDB Lab), Deep Tech: The New Wave

  • Share of global lithium RESOURCES, not reserves. The report says "reserves"; that is an error (ledger #2).
  • Carry as a ~700–865k headcount range, not a point value: RICYT reports "exceeding 700 thousand" (2024) against the IDB's 865k. FTE runs materially lower than headcount (ledger #4).

Methodology: renewables 65% CONFIRMED (Ember GER 2026). biodiversity 42% is within the established range, UNEP/WEF cite ~40% of global biodiversity (up to ~60% of terrestrial life on a broader measure); keep 42% with the range noted (ledger #1). lithium 58% is RESOURCES not reserves (ledger #2). researchers 865k → carry as ~700–865k range (RICYT ~700k vs IDB 865k; headcount/FTE, ledger #4). researchers value is in thousands.

Yet LATAM is singularly primed for Deep Tech, the region’s core endowments.

Beyond the momentum of its resources, Latin America offers compelling opportunities for greenfield FDI, projects where companies build new facilities from the ground up rather than acquiring existing assets. Greenfields are attractive given abundant land and natural resources, improving logistics links, and the ability to tailor plants to modern standards. For aerospace specifically, select geographies near the equator offer orbital-mechanics advantages for certain launch profiles, adding a niche location edge.

According to the UNCTAD World Investment Report 2025, developing countries attracted more than $530 billion in greenfield digital-economy projects between 2020 and 2024. Close to 80% of this investment was concentrated in just ten countries, with Brazil and Mexico the only Latin American economies represented.

Amid intensifying U.S.–China competition, near-shoring, relocating operations to nearby countries rather than distant off-shore locations, is disrupting the decades-old model of prioritizing lowest-cost production, instead emphasizing supply-chain resilience and regional proximity. Latin America has emerged as a prime beneficiary as companies in North America move "from pure cost efficiency toward resilience, redundancy, and regional integration," according to Fausto Carbajal.

Mexico leads LATAM’s nearshoring wave, thanks to its geographic proximity, free-trade agreements, skilled and cost-competitive labor, and extensive logistics network, advantages expected to favor semiconductors, automotive, electrical equipment, medical devices, agribusiness, and food. Santander Mexico estimates near-shoring could drive FDI to levels exceeding remittances as soon as 2025. Beyond Mexico, countries like Colombia are becoming specialized IT hubs, creating complementary regional ecosystems.

Latin America possesses the natural endowments, human capital and early-stage funding momentum to turn Deep Tech from a remote aspiration into a practical engine of inclusive growth.

Understanding this dual reality, the entrenched gaps and the emergent assets, is the first step. The pages that follow map the region’s structural challenges, spotlight global case studies of successful leap-frogging, and lay out the policy, capital-market and talent interventions to close the region’s long-standing "LATAM Discount."

06 / 29 6 min

LATAM’s Deep Tech Landscape

p. 25

The database used for this analysis comprises 2,566 LATAM startups. This count differs from our initial estimate of over 5,000 after filtering; a fuller explanation is in the Methodology section.

For context, the IDB mapped 340 Deep Tech startups in LATAM in 2023, and EMERGE reported over 1,300 in 2025. Our higher count reflects an expanded sector scope that includes AI and cryptography, two verticals that have grown sharply in the last five years. This underscores the limits of closed, proprietary databases maintained in parallel by different actors, divergent definitions, methods, and limited auditability drive many of the discrepancies across reports. The robust path is a regional, open, versioned, auditable dataset with a shared taxonomy, transparent inclusion criteria, and a public correction/contribution workflow.

The main discrepancy comes because we expanded the scope of the database to AI and cryptography, two verticals that have grown significantly in the last two years. This is work in progress and will expand as we validate additional rounds.

# Geographical analysis

LATAM’s Deep Tech landscape is sharply concentrated: Brazil hosts about 41% of all startups, driven by São Paulo’s 29% share, while Mexico, Argentina, Chile and Colombia, together with their leading capitals, gather most of the rest, leaving a long tail of smaller countries and cities that underscores both the ecosystem’s strength and its geographic imbalance.

A highly concentrated map
ventures mapped
Brazil1,04840.8%
Mexico35814%
Argentina25610%
Chile2519.8%
Colombia2198.5%
Rest of LATAM43416.9%

Brazil hosts 41% of the region’s ventures, more than the next four countries combined. The “Big 5” account for 83% of everything mapped.

As originally publishedAs of March 2025Report p.25

The figure as the report published it, September 2025.

SourcesLatin American Dynamism Project (LADP), Accelerating Deep Tech in Latin America; Tracxn Technologies, Tracxn, LATAM deep tech company database (LADP extract); EMERGE (Emerge Brasil) & Cubo Itaú, Radar Deep Tech LATAM 2025

Methodology: LADP/Tracxn count and share. ledger #25/#26: EMERGE's independent mapping disagrees sharply (Brazil 72.3% vs 40.8%; different rank order). Neither is "the" number, a definitional gap, not an error.

Top countries by number of startups. Source: LADP analysis, Tracxn data.
  • Brazil dominates with 1,048 Deep Tech startups, about 40.8% of the entire regional database. Its share is larger than the next four countries combined.
  • Mexico (358, 14%), Argentina (256, 10%), Chile (251, 9.8%) and Colombia (219, 8.5%) form a solid second tier. Together with Brazil, these five countries host 83% of all mapped companies.
  • Beyond the "Big 5," a long tail of emerging hubs, Panama, Peru, Puerto Rico, Uruguay and Ecuador, offers earlier-stage, less-crowded markets.

Cultivating a distributed tech ecosystem depends on a dual approach: reinforcing major existing hubs, like São Paulo and Mexico City, while nurturing new ecosystems across the region, such as Uruguay and Costa Rica. Two strategies documented in Chile and Colombia are relevant: mixed cohorts that place international and local founders in the same programs to maximize peer-learning, and ecosystem-as-a-service (EaaS) operators that provide shared services so startups can progress faster.

  • São Paulo is Latin America’s largest Deep Tech hub with 329 startups, roughly 29% of all ventures in the top-10 cities, more than the next three hubs combined.
  • Buenos Aires, Santiago and Mexico City form a strong second tier; together with São Paulo they account for 63% of the mapped activity.
  • Bogotá anchors the Andean corridor, but its scale remains half that of the tier-two group, signalling room for growth of seed and Series A funding.
  • Brazil fields five of the top-ten hubs, São Paulo plus Rio de Janeiro, Curitiba, Belo Horizonte and Porto Alegre, highlighting powerful domestic network effects.

# Funding stage and tickets

Our analysis indicates a significant funding gap. While capital flow has rebounded since the 2021 pandemic and big-tech crisis, few startups progress beyond Seed rounds as of 2025. This is consistent with IDB findings: up until 2022, 65% of Deep Tech startups in LATAM were still in pre-seed and seed phases, having raised less than $1 million, while a scant 8% had progressed to Series B (those exceeding $10 million).

The ecosystem is heavily front-loaded: 72% of ventures are still at Seed stage, and only 19% have secured a Series A. Dramatically, only 22 startups (10%) have secured a Series B round or beyond, confirming a steep funnel from validation to scale-up. According to Dealroom, even as overall Deep Tech funding remained robust at $138 million in 2024, not a single Series B or later round closed in LATAM. Our data reveals the median round size scales from US$0.6M (Seed) to US$8.3M (Series A), then leaps to US$17M (Series B) and US$100M (Series C).

The scale-up funnel
$0.6M median round
$8.3M median round
$17M median round

The ecosystem is front-loaded: 72% of ventures sit at Seed, only 19% reach Series A, and just 22 (10%) have raised Series B or beyond. Median ticket sizes jump an order of magnitude at each stage.

As originally publishedAs of March 2025Report p.28

The figure as the report published it, September 2025.

SourcesLatin American Dynamism Project (LADP), Accelerating Deep Tech in Latin America; Tracxn Technologies, Tracxn, LATAM deep tech company database (LADP extract); Inter-American Development Bank (IDB Lab), Deep Tech: The New Wave

Methodology: Share of ventures by stage (LADP/Tracxn) with median ticket in USD m. ledger #35: the report text (10%, "22 startups") contradicts this chart's Series-B share (9%).

Funding stage by number of startups and median ticket. Source: LADP analysis, Tracxn data.

Over the past five years the number of funding rounds has increased, yet the average cheque size has fallen dramatically from its 2021 high. In 2021, only 27 rounds were recorded, coinciding with unusually large tickets. In 2022, deal activity more than doubled as capital dispersed into a wider set of companies. In 2023 the round count fell 30% from 2022 and, more dramatically, the average check dropped 70%. In 2024 activity rebounded to its highest level by round count, yet still skewed toward early-stage financing, confidence in Deep Tech fundamentals returned faster than appetite for large growth cheques, leaving the Series B–C "scale-up gap" even wider.

# Sector coverage

Given the absence of sector-level disaggregation in our data, we use the IDB’s Deep Tech: The New Wave as the reference framework. By 2023, Biotechnology (61%) dominated LATAM’s Deep Tech, followed by Artificial Intelligence (11%). Together they represented 72% of regional startups, reflecting the critical role these technologies play in sustainable agriculture, food security, and healthcare.

LATAM deep tech by sector
share of ventures
Biotechnology61%
Artificial Intelligence11%
Nanotechnology6%
Cleantech5%
Spacetech4%
Advanced Mobility4%
Robotics2%
Advanced Manufacturing2%
Healthtech2%
Advanced Materials1%
Medical Devices & Others1%

Biotechnology and AI alone account for 72% of mapped ventures, a reflection of the region’s biological-sciences talent and biodiversity.

As originally publishedAs of 2023Report p.30

The figure as the report published it, September 2025.

SourceInter-American Development Bank (IDB Lab), Deep Tech: The New Wave

  • The report prints "<1%"; charted at its upper bound. Named sectors sum to 99%.

Methodology: IDB 2023 sector split by COMPANY COUNT, CONFIRMED still current by EMERGE Radar 2025 (biotech 61% / AI 11% both editions). But it measures the stock, not the flow: see the new `aiMomentum` dataset, AI is 11% of companies yet ~70% of rounds by 2023–2025 vintage. Pair the two on the site (ledger #42).

Percentage of LAC Deep Tech startups by technology sector. Source: IDB, Deep Tech: The New Wave.

According to the IDB, the prevalence of biotech aligns with the region’s abundant specialized talent in biological sciences, the international competitiveness of the agricultural sector, and remarkable biodiversity. Costa Rica and Argentina illustrate this concentration, with 97% and 80% of their respective Deep Tech ecosystem value coming from biotech. Establishment Labs, a Costa Rica–based biotech company, stands as the region’s most valuable player. SOSV/IndieBio reported a 72% gross average return on LATAM Deep Tech startups between 2015 and 2023.

Beyond these two leading areas, the landscape includes Nanotechnology (6%), Clean Tech (5%), Spacetech (4%), Advanced Mobility (4%), Robotics (2%), Advanced Manufacturing (2%), Health Tech (2%), Advanced Materials (1%), and Medical Devices & Others (<1%). While these sectors carve out promising niches, the region’s Deep Tech ecosystem remains starved for capital, venture funding for R&D in LATAM is roughly 13 times lower than in China and 70 times lower than in the U.S., a shortfall that chokes off early-stage growth.

# Who is investing

By 2023, there were 65 VC funds with at least one Deep Tech investment in LATAM, according to the IDB, both regional and international. By 2025, Hello Tomorrow’s Deep Tech Investor Mapping had identified nearly 40 VC funds active in the region. Beyond updating coverage, the analysis should move from presence to intensity: quantify how often each investor backs Deep Tech startups, at which stages and ticket sizes, their follow-on behavior, and the graduation rate of portfolio companies. It should also isolate corporate venture capital activity and add family offices and sovereign wealth funds, which emerged in our interviews as increasingly relevant co-investors.

07 / 29 4 min

Startup Success Stories

p. 34

The science is already shipping. From extremophile microbes to Earth-observation constellations, LATAM Deep Tech ventures are reaching global markets today, concrete proof points that demystify the journey from lab to market.

Earth Observation AR

Satellogic

A constellation of 34 high-resolution satellites delivering affordable geospatial data for real-time monitoring of global environmental and economic activity. Backed by Liberty Strategic Capital, Tencent and the IDB.

Medical Technology CR

Establishment Labs

Maker of minimally invasive, next-generation Motiva® breast implants, 25 patents across 25 jurisdictions, distribution to 70+ countries. NASDAQ-listed at a $1.8bn valuation, the region’s most valuable medtech venture.

Industrial AI BR

Tractian

Integrated hardware, software and AI that democratize predictive maintenance for industrial operations. Raised a $120M Series C led by Sapphire Ventures; backers include General Catalyst and Y Combinator.

Biotechnology AR

Puna Bio

Biological inputs for agriculture derived from extremophile microbes found in high-altitude deserts, boosting yields and soil health while cutting chemical fertilizer use. Backed by the Gates Foundation and SOSV/IndieBio.

Identity / Cryptography AR

Auth0

Standards-based authentication and authorization for modern applications. Raised $210M+ across multiple rounds at a $1.92bn valuation, then acquired by Okta in 2021, a landmark regional exit.

Environmental Tech CL

Photio

Nanoparticle additives that turn urban surfaces into air-purification agents, degrading atmospheric pollutants in light. Deep Tech Pioneer & Track Winner at Hello Tomorrow’s 2023 Challenge.

Biotechnology BR

Nintx

Translates inter-species biology from plants and microorganisms into multi-target therapies acting on biological pathways and the gut microbiome, drawing on Brazilian ecosystems.

Biotechnology BR

Symbiomics

Microbiome, genomic and machine-learning platforms that develop biological products for sustainable agriculture, raising productivity while reducing agrochemical reliance and sequestering carbon.

Biotechnology AR

M4Life

A CONICET spinoff applying biologically trained microbes to seeds for soil restoration, deforestation prevention and CO₂ capture. Deep Tech Pioneer & Finalist at Hello Tomorrow 2024.

Scientific Instrumentation BR

FabNS

Tip-Enhanced Raman Spectroscopy for chemical imaging at nanometric resolution, at a third of market price. A UFMG spinoff recognized as MIT Innovators Under 35.

Construction Technology CL

Strong by Form

Bio-inspired digital manufacturing of high-performance structural wood components that can replace steel, concrete and aluminum. Hello Tomorrow 2022 Track Winner.

Energy AI CL

Splight

Grid-operations AI that tackles energy curtailment and congestion to maximize renewable integration. Raised a $12M seed led by noa, with EDP Ventures and UC Berkeley Foundation.

Clean Technology MX

Sistema.bio

Biodigester technology that converts organic waste into clean energy and fertilizer for farmers across a dozen LATAM countries. Backers include AXA IM and EcoEnterprises Fund.

Biotechnology UY

Antarka

DNA-repair enzymes from Antarctic extremophiles for skincare, achieving 100% UV-damage repair in ex-vivo human skin. A Universidad de la República spinoff backed by SOSV/IndieBio.

Argentina · Cryptography · Acquired

Auth0

Auth0 was founded to simplify and secure authentication and authorization for modern applications. From its inception the platform embraced open standards, JSON Web Tokens, OpenID Connect, SAML, so developers could integrate identity features without lock-in.

By mid-2020 it had raised over US$210 million across multiple rounds, culminating in a US$120 million Series E led by Salesforce Ventures at a US$1.92 billion valuation. In March 2021, Okta acquired Auth0.

Founded
2013
Tech maturity
TRL 9
Total funding
USD 332.3M
Brazilian roots · Industrial AI · Series C

Tractian

Tractian combines integrated hardware, software, and AI to democratize predictive and preventive maintenance for industrial operations, helping companies optimize equipment performance and reduce downtime.

The company has raised $200 million in total funding, with a notable $120 million Series C led by Sapphire Ventures. Previous backers include General Catalyst, Next47, NGP Capital, and Y Combinator.

Tech maturity
TRL 9
Total funding
USD 185.6M
Brazil · Biotechnology · Series A

Nintx

Nintx translates inter-species biology from plants and microorganisms into multi-target therapies that act on biological pathways and gut-microbiome modulation, leveraging natural mechanisms from Brazilian ecosystems.

Following a $3 million seed round in 2022, the startup closed a $10 million Series A led by Brazilian investors Pitanga, Ecoa Capital, and MOV Investimentos, plus a $2.5 million FINEP grant.

Founded
2021
Tech maturity
TRL 9
Total funding
USD 15M
Florianópolis · Biotechnology · Series A

Symbiomics

Symbiomics uses advanced microbiome, genomic, and machine-learning platforms to develop biological products for sustainable agriculture, increasing productivity while reducing reliance on agrochemicals.

With $4.11 million raised across seed rounds, the company secured backing from The Yield Lab Latam, Vesper Ventures, MOV Investimentos, Baraúna Investimentos, and Ecoa Capital.

Founded
2021
Tech maturity
TRL 9
Total funding
USD 2M
Belo Horizonte · Scientific instrumentation · Seed

FabNS

FabNS develops advanced nanoscale analysis using TERS (Tip-Enhanced Raman Spectroscopy), combining patented nanoantenna tips with probe microscopy for chemical imaging at nanometric resolution, at one-third of market price.

A spinoff from the Federal University of Minas Gerais, it was selected as a Deep Tech Pioneer in Hello Tomorrow’s 2024 Challenge and recognized as MIT Innovators Under 35.

Founded
2020
Tech maturity
TRL 9
Huechuraba, Chile · Environmental tech · Accelerator

Photio

Photio creates nanoparticle additives that transform urban surfaces into air-purification agents, degrading atmospheric pollutants when exposed to light through synergistic photocatalysts.

Selected as Deep Tech Pioneer & Track Winner in Hello Tomorrow’s 2023 Challenge, the startup received Startup Chile Growth support and won the Premio de Innovación PwC.

Founded
2019
Tech maturity
TRL 9
Santiago · Construction tech · Series A

Strong by Form

Strong by Form uses bio-inspired digital manufacturing to create high-performance structural wood components through computational optimization and robotic manufacturing, enabling wood to replace steel, concrete, and aluminum.

Selected as Deep Tech Pioneer & Track Winner in Hello Tomorrow’s 2022 Challenge, the company received Leonard SEED Program support and Latam Cleantech 25 recognition.

Founded
2018
Tech maturity
TRL 7
Total funding
USD 6.2M
Chile · Energy technology · Seed

Splight

Splight develops advanced grid-operations AI that addresses energy curtailment and grid congestion, optimizing electrical-grid performance to maximize renewable-energy integration.

The startup raised $12 million in seed funding led by noa (formerly A/O), with participation from EDP Ventures, Elewit, Draper Cygnus, Ascent Energy Ventures, and the UC Berkeley Foundation.

Tech maturity
TRL 9
Total funding
USD 26.1M
Costa Rica · Medical technology · IPO

Establishment Labs

Establishment Labs manufactures minimally invasive, next-generation breast implants under the Motiva Implants® brand, with 25 patents and 200 patent applications across 25 jurisdictions, distributing to over 70 countries.

With $121 million raised across eight rounds and a NASDAQ listing at $1.8 billion valuation, it is Latin America’s most valuable medical-technology venture. Key investors include Madryn Asset Management, JW Asset Management, and Crown Predator Holdings.

Founded
2004
Tech maturity
TRL 9
Total funding
USD 580.7M
Mexico · Clean technology · Series B

Sistema.bio

Sistema.bio provides biodigester solutions for sustainable waste management and renewable-energy generation, converting organic waste into clean energy and nutrient-rich fertilizer across Latin America.

Operating hubs in Mexico and Colombia with partnerships across a dozen LATAM countries, it raised $22.8 million across three Series B rounds between 2024–2025. Investors include KawiSafi, AXA Investment Managers, EcoEnterprises Fund, and Novastar Ventures.

Tech maturity
TRL 9
Total funding
USD 22.8M
Montevideo · Biotechnology · Accelerator

Antarka

Antarka develops DNA-repair enzymes from Antarctic extremophile organisms for skincare, achieving 100% UV-damage repair efficacy in ex-vivo human skin using visible-light-activated photolyases.

Selected as Deep Tech Pioneer in Hello Tomorrow’s 2023 Challenge, the Universidad de la República spinoff received backing from SOSV/IndieBio and Grid Exponential.

Founded
2023
Tech maturity
TRL 8
Total funding
USD 400K
08 / 29 5 min

Deep Tech Investment in LATAM

A promising but still nascent ecosystem

p. 40

By 2023, investment in LATAM increased by nearly 600% between 2019 and 2023, rising from under USD 300 million to USD 2 billion in just four years, according to the IDB’s Deep Tech: The New Wave. As of September 2024, cumulative investment had grown by an additional USD 536 million, bringing the regional total to roughly USD 2.54 billion.

Even at this higher level, LATAM still trails other regions: roughly USD 13 billion in Asia, USD 14 billion in Europe, and USD 52 billion in the United States. In macroeconomic context, those volumes correspond to about 0.04% of Latin America’s GDP, versus approximately 0.08% in Europe, 0.20% in Asia, and 0.22% in the U.S. Per capita, Latin America’s $15.25 per-person investment is higher than Asia’s modest $2.7, but still half of Europe’s $31 and a fraction of the United States’ $153.

Per-capita deep tech investment
USD per capita
United States$153
Europe$31
Latin America$15
Asia$3

LATAM invests half of Europe’s level and a tenth of the United States’, per person, in USD.

As originally publishedAs of September 2024Report p.40

The figure as the report published it, September 2025.

SourcesLatin American Dynamism Project (LADP), Accelerating Deep Tech in Latin America; Inter-American Development Bank (IDB Lab), Deep Tech: The New Wave; Sling Hub & Itaú, LATAM Startup Market 2024 in Review; Atomico, State of European Tech Report 2024

Methodology: LADP calculation from cumulative regional deep tech investment ÷ population. ledger #67: denominators are inconsistent (Asia = continent, Europe ≈ EU). Recompute with stated population bases before refreshing.

Per-capita Deep Tech investment (USD). LATAM invests half of Europe’s level and ~10× lower than the U.S. Sources: IDB, SlingHub, Atomico; LADP calculations.
Cumulative investment by region
USD billions
United States$52.0B
Europe$14.0B
Asia$13.0B
Latin America$2.5B

In absolute terms the gap is starker still: roughly USD 2.5bn for all of LATAM.

As originally publishedAs of September 2024Report p.40

The figure as the report published it, September 2025.

SourceInter-American Development Bank (IDB Lab), Deep Tech: The New Wave

Methodology: Cumulative-to-Sept-2024 per Science|Business. ledger #65. NOT refreshed to a comparable current series ON PURPOSE: public 2025 figures use incompatible deep tech taxonomies (Tracxn US ~$179bn vs Dealroom Europe $20.3bn, not comparable) and refreshing across them would repeat the report's own error. Scale anchor for the chart caption: Europe alone was $20.3bn of ANNUAL deep tech VC in 2025 (Dealroom), against the report's $14bn CUMULATIVE, so label units explicitly and treat the four bars as a 2024 cumulative snapshot, not a live comparison. Global deep tech ~$250bn in 2025; US ~45% of deals, Europe ~30%, Asia >20%.

Cumulative investment by region (USD bn).

This illustrates that while other regions have more mature Deep Tech ecosystems, Latin America has an immense and largely untapped opportunity for both capital and innovation. Looking ahead, the IDB projected in 2023 a twentyfold increase in VC investment into LATAM Deep Tech startups over the next decade, underpinned by a growing pool of researchers and engineers, cost advantages, lower early-stage valuations with attractive return profiles, and the region’s exceptional biodiversity.

The model rests on three points: Europe’s deep-tech VC 18× growth from 2012 to 2022, LATAM’s general 20× VC growth between 2012–2022, and LATAM’s 1.8× Deep Tech growth from 2020 to 2022. We present this as a high-end scenario, credible but contingent on progress in talent retention, later-stage capital depth, regulatory coherence, and exit pathways.

From $300m to a 20× horizon
USD billions, cumulative
$0.00B$1.00B$2.00B$3.00B201920232024
20×projected by 2032

Investment grew ~600% between 2019 and 2023, reaching USD 2.5bn by late 2024. The BID projects a 20× expansion of the ecosystem by 2032.

As originally publishedAs of September 2024Report p.41

The figure as the report published it, September 2025.

SourcesInter-American Development Bank (IDB Lab), Deep Tech: The New Wave; Sling Hub & Itaú, LATAM Startup Market 2024 in Review; Latin American Dynamism Project (LADP), Accelerating Deep Tech in Latin America

Methodology: Cumulative LATAM deep tech investment. ledger #63/#64: extend through FY2025 and H1-2026; the $2.54bn endpoint mixes an annual flow into a cumulative stock.

VC investment trajectory and the IDB’s 20× decade projection. Source: IDB, Deep Tech: The New Wave.

In 2024, after three years of decline, primarily due to the pandemic and the "big tech crisis", the funding landscape for LATAM tech startups showed positive signs again. According to the LATAM Startup Market 2024 in Review report by SlingHub & Itaú, 2024 marked the first year since 2021 that LATAM’s tech industries experienced year-over-year growth, reaching 37%. Market funding across all tech sectors increased from USD 6.4 billion to USD 8.8 billion.

LATAM’s tech investment rebounded 37% YoY in 2024, marking the first year of recovery since 2021 and signaling renewed investor confidence across sectors.

A closer look reveals that Deep Tech is the most steadily growing area. Deep Tech emerged as the third-largest category within all tech industries, securing USD 536 million of funding, 6% of the overall total, placing it just behind energy (13%) and fintech, which dominated with 55% of market funding. Although a small percentage overall, Deep Tech grew the most year over year, accounting for a 219% overall growth increase. On equity funding the trend is similar: Deep Tech lags Fintech (41%) in volume and equals Energy at 11%, yet was the highest year-over-year grower in equity funding volume in 2024, with 189% growth.

Where 2024 funding went
share of total tech funding (%)
Fintech55%
Energy13%
Deep tech6%
Other verticals26%

Deep tech took 6% of Latin America’s tech funding in 2024, USD 536M of USD 8.8bn. Fintech still dominates the total, but deep tech’s share is climbing.

As originally publishedAs of 2024Report p.43

The figure as the report published it, September 2025.

SourceSling Hub & Itaú, LATAM Startup Market 2024 in Review

Methodology: Total funding share 2024. Report names fintech 55, energy 13, deep tech 6; "other" 26 is the remainder to 100. Fintech ~58% at LTM Q2-2026 (Dealroom), persists (ledger #71).

Leading tech markets by total funding volume raised in 2024. Source: SlingHub, LATAM Startup Market 2024 in Review.
Equity funding tells a sharper story
share of equity funding (%)
Fintech41%
Deep tech11%
Energy11%
Other verticals37%

By equity funding, deep tech reaches 11%, level with energy and second only to fintech. Investors are already putting real ownership behind the sector.

As originally publishedAs of 2024Report p.43

The figure as the report published it, September 2025.

SourceSling Hub & Itaú, LATAM Startup Market 2024 in Review

Methodology: Equity funding share 2024 (ledger #74). Report names fintech 41, deep tech 11, energy 11; "other" 37 is the remainder.

Leading tech markets by equity funding volume raised in 2024. Source: SlingHub.
The fastest-growing sector in the region
+219%Deep tech funding growth
+189%Equity funding growth
+37%Overall tech rebound
4×Corporate VC growth (2020–24)

In 2024 deep tech outgrew every other tech vertical in LATAM, by funding and by equity.

As originally publishedAs of 2024Report p.43

The figure as the report published it, September 2025.

SourcesSling Hub & Itaú, LATAM Startup Market 2024 in Review; Dealroom.co, Deep Tech Overview: Latin America

Methodology: YoY 2024-over-2023 growth (Sling Hub) plus CVC 4× (Dealroom, ledger #76/#127). Two cycles old; refresh to FY2025.

Headline growth figures across the ecosystem.

# Gaps to become international unicorns

While Deep Tech in LATAM boasts exciting pockets, the region remains dramatically undercapitalized. R&D funding is roughly 13× lower than in China and 70× lower than in the U.S. This shortfall is structural. In advanced economies like the US and EU, companies fund over 60% of R&D (nearly 80% in China); in LATAM, businesses cover only about 35%, while governments provide roughly 60%.

Who funds the research
business-funded share of R&D (%)
Latin America35%
United States & Europe60%
China80%

Business covers about 35% of R&D in Latin America, against 60% or more across the United States and Europe and nearly 80% in China. Thin private research funding is a structural brake on deep tech.

As originally publishedAs of September 2025Report p.48

The figure as the report published it, September 2025.

SourceECLAC / CEPAL, Ciencia, tecnología e innovación: cooperación, integración y desafíos regionales (LC/TS.2022/156)

Methodology: ECLAC Graph I.3, 2019 data (ledger #75/#97). us-eu government = 25 is the midpoint of the report's "20–30" range. Superseded framing: UIS 2026 gives LAC R&D at 0.57% of GDP vs 1.92% global, a stronger level comparison than this composition split.

R&D expenditure by funding sector, 2019 (%). Source: ECLAC.
09 / 29 3 min

From the LATAM Discount to Fair Value

p. 45

The "LATAM Discount" refers to the phenomenon where startups and companies in Latin America are often valued lower than counterparts in the United States, Europe or other emerging markets, despite similar or even superior metrics. The discount is attributed to perceived risks, political instability, economic volatility, and regulatory challenges, that deter international investors.

Even in traditional equities markets, Latin American equities have traded at a significant discount to global averages and Emerging Markets in recent years. The MSCI LATAM Index, which captures large- and mid-cap representation in Brazil, Chile, Colombia, Mexico, and Peru, suggests LATAM is trading at a –51% discount compared to the world, above the historical average of –13.9%. According to Itaú BBA, "this can be partially explained by the rising relevance of tech companies in global indexes, at a higher pace than EMs, while LATAM has virtually little exposure to this sector." Against other Emerging Markets, LATAM trades at a –27.7% discount as of 2024.

The LATAM Discount
valuation gap (%)
−51.0%vs. the world
historical average−13.9%
vs. emerging markets−27.7%
vs. the world−51.0%

Latin American assets trade far below global and emerging-market peers, and well beyond the historical average. The report’s core claim: this is a solvable mispricing.

Verified against the primary sourceAs of 2024Report p.45

The figure as the report published it, September 2025. It has since been re-verified and moved; switch to Current to see it.

SourceItaú BBA Equity Strategy Team, Latam & Brazil Equity Strategy: Thematic Book

Methodology: REFRESHED. Price-to-book discount computed from the MSCI EM Latin America Index factsheet, 30 Jun 2026: LATAM P/BV 1.99 vs ACWI 3.86 = −48.4% (world); vs EM P/BV 2.58 = −22.9%. Narrowed from the Itaú BBA 2024 read (−51% / −27.7%) after LATAM rallied +55.67% in 2025 (ledger #77/#78). Still a market figure that moves daily, asOf is the factsheet date.

Historical price-to-book premium/discount: LATAM vs. World. Source: Itaú BBA, Latam & Brazil Equity Strategy: Thematic Book.

# Key exposures that drive risk and return

The 2025 MSCI Index compares the factor exposures of LATAM and other EMs like China or India against a global benchmark (MSCI ACWI IMI). From the six main factors, Value, Low Size, Momentum, Quality, Yield and Low Volatility, LATAM is especially overexposed to Volatility, represented by commodity exposure, macroeconomic swings and political risks. This is typically negative and can deter global equities investors. In parallel, LATAM lags behind other emerging markets and the global benchmark on Quality and Momentum, indicating fewer high-quality balance sheets or fewer stocks with strong price momentum. A negative Low Size tilt suggests the index is more concentrated in large-cap stocks.

This phenomenon brings us to the pivotal question: why bother investing in emerging markets? After all, investors might remain in the U.S., where returns are stable and fixed-income rates exceed 5%. As one observer put it, "the big issue seems to be whether emerging returns are enough to drag U.S. and Western funds away from an increasingly comfortable home bias." Nevertheless, this report and broader data indicate compelling reasons to invest precisely at this juncture.

The LATAM discount represents a temporary mispricing driven by solvable structural factors, regulatory uncertainty, limited market liquidity, and information asymmetries, rather than permanently inferior fundamentals.

As these factors improve through institutional development, enhanced transparency, and deeper capital markets, the region’s valuations should converge toward their intrinsic value, creating attractive risk-adjusted returns without requiring speculative premiums.

The question is shifting from "Why Latin America?" to "Why haven’t we invested more?"

Cristián Hernández Manager, Zentynel
10 / 29 5 min

Recommendations: Closing the LATAM Discount

20 recommendations across three arcs

p. 49

What follows are 20 concrete recommendations across three arcs: what companies must do to become investable (Market Readiness), what unlocks investor confidence (Investor Readiness), and the regional coalition that ties it together, plus five further-research initiatives.

Market Readiness

01

Venture Building, Train, Fund, Validate

Scientific founders often lack core entrepreneurial skills, embed venture building as mainstream in universities and research institutes. Launch structured matchmaking to build balanced science–business founding teams, and plug them into sequenced pipelines of non-dilutive grants and CVC pilot lanes so they can validate products in real-world settings.

02

Metrics & Success Stories, Deep Tech KPI Frameworks

Investor skepticism arises from a lack of performance data and tangible success narratives. Collect, validate, and publicize key metrics (IRR, exit multiples, time-to-market) alongside high-impact regional case studies to illustrate Deep Tech ROI potential and enable like-for-like comparisons across markets.

03

Showcase & Visibility, Educate Privately, Convene Publicly

Limited understanding of Deep Tech investment constrains funding availability. Launch targeted educational initiatives for VCs, family offices, and CVCs to demystify Deep Tech fundamentals, showcase regional ROI data, and build confidence for larger, strategic funding commitments.

04

Impact-Driven Narratives, Deep Tech for SDGs

Lab-driven founders default to dense technical explanations. Embed structured storytelling programs to translate complex science into clear, emotionally resonant stories of global impact, turning bench-top breakthroughs into funding catalysts. Embedding frameworks like the SDGs is a plus.

05

Global Mindset, Language First, Structure Next

Small markets, fragmented rules, FX volatility, and language barriers nudge founders toward local-first. From day one, require English upskilling for founders and technical leads and adopt English-first artifacts, plus international structures (Delaware/UK holding with local subsidiaries, early USPTO/EPO filings) to reduce diligence friction and speed cross-border commercialization.

Investor Readiness

06

R&D Skepticism, Regional International Scientific Advisory Boards

Persistent doubts about LATAM’s early-stage science slow diligence and capital. Establish vertical-specific Regional International Scientific Advisory Boards pairing global experts with top LATAM scientists to run TRL-3–5 peer reviews, issue endorsement seals, provide targeted support, and publish an annual "State of Deep Tech Science" brief.

07

Uneven Clinical Trials, Alignment Through Interoperability

Early-stage ventures struggle to attract international capital due to country-specific regulations. Adopt a "global-first" compliance strategy, aligning with the FDA/EMA from day one, while exploring Special Economic Zones to compress permit cycles, and advocate for mutual recognition of scientific approvals across LATAM states.

08

Regulatory Portability, The 34th Regime

LATAM’s policy landscape is a patchwork. Champion a voluntary, pan-LATAM "34th Regime" single-startup status, modeled on Europe’s 28th, for mutual recognition, regional sandboxes, standardized digital filings, and portable approvals; constitute it via a plurilateral (CELAC / Pacific Alliance) and pilot on existing rails.

09

Corporate Venture Capital, Matchmaking Bridges & Observatory

CVC backup is no longer optional. Stand up a neutral, region-wide CVC Bridge to professionalize matchmaking through sector pitch days, diligence-ready data-room templates, and pilots on corporate testbeds. Anchor it with a CVC × Deep Tech Observatory tracking participation, time-to-deal, survival, and procurement conversion.

10

Social Clusters, Guilds & Ecosystem-as-a-Service

R&D must be paired with social infrastructure. Beyond shared labs, build curated, mixed domestic–international founder cohorts and consolidate Ecosystem-as-a-Service operators that convene academia, founders, corporates, policymakers, and governments; run recurring peer forums and clinics and maintain warm-intro circuits.

Regional Coalition

11

Anchor Public R&D to a Sovereign-Tech Agenda

Fragmented, short-term public funding limits LATAM’s strategic impact. Work with public institutions to place strategic Deep Tech fields on the same footing as critical infrastructure, rolling out upgraded Special Economic Zones, 1:1 matching-funds, and sovereign co-investment vehicles that channel long-term R&D budgets.

12

Pensions, A Fund-of-Funds for Domestic Deep Tech

On top of public funding, establish an independently managed fund-of-funds that mobilizes a slice of pension assets into domestic Deep Tech via vetted specialist GPs. Modeled after France’s Tibi initiative and the UK’s Mansion House reforms, advocate for local co-investment and procurement links, turning public budgets into catalytic patient capital.

13

Geopolitical Lens, Strategic Autonomy

The tech order is being reordered, China’s scale-up, U.S.–EU realignments, and the rise of middle powers create parallel tracks for capital, supply chains, and standards. Establish a dedicated working group to map flows, stress-test partnerships, and broker corridors (SEZs, joint labs, procurement pilots, standards MOUs) with superpowers and middle powers alike. Publish quarterly heatmaps and deal playbooks.

14

Research & Visibility, Open Data Commons & Grants Portal

LATAM lacks a shared evidence base and a clear window into non-dilutive capital. Build an open-access data commons, standardized stats, deal/IP registries, dashboards, and case studies, to cut diligence friction, paired with a unified grants portal that normalizes funding types, ticket sizes, eligibility, and deadlines, with AI application assistants.

15

Forge a Pan-LATAM Deep-Tech Forum

LATAM’s event surge is fragmented; launch a single, rotating flagship co-branded by leading funds, accelerators, and alliances to pool sponsors, attract international LPs/CVCs, and project one regional narrative. Anchor the forum with annual KPI releases so it becomes the region’s measurable, go-to platform for deep-tech scale.

Further Research Initiatives

16

Extended Funders Mapping

Build a living registry of VC/CVC/family offices/sovereign funds active in LATAM Deep Tech. Deliver a directory with tags (sector, stage, ticket, geo), an investor-roadshow calendar, and a submission form, updated quarterly via web-scrapes, press tracking, and partner validations.

17

Deep Tech LATAM Discount Index

Across all sectors, LATAM assets trade at –50% vs. global peers. Deep Tech likely mirrors this gap, yet no standardized index exists. Build an MSCI-style, repeatable framework to quantify valuation gaps and frictions, with an open methodology fed by regulator stats, deal-level data, and founder/investor surveys.

18

CVC Survival Effect

In Europe, CVC-backed startups show roughly half the bankruptcy rate of non-CVC peers. LATAM lacks an equivalent measure. Measure survival, time-to-next-round, and bankruptcy rates for CVC-backed vs. non-CVC startups, producing a matched dataset with hazard ratios and sector breakdowns.

19

Internal Rate of Return

In Europe and the U.S., Deep Tech funds outperform traditional tech by 7% in average net IRR (McKinsey). LATAM lacks comparable, region-specific data. Establish a LATAM benchmark to contextualize performance and strengthen the case for channeling patient capital into deep tech.

20

$1 Test, LATAM vs. Global Gross Average Return

SOSV reported a 72% gross average return on its LATAM Deep Tech portfolio between 2015–2023, but it is a single-manager statistic. To make a credible regional case, build a $1 ROI Test comparing LATAM to matched US/EU/Asia baskets, and report MOIC/ROI with confidence bands.

Open the interactive recommendations explorer Filter all 20 by theme and audience.
11 / 29 4 min

Venture Building: The Science-to-Startup Pipeline

Recommendation 01 · Market Readiness

p. 55

One of the most critical challenges for Deep Tech startups lies in bridging the gap between scientific innovation and business execution. Many ventures are founded by brilliant scientists who face a steep learning curve when shifting into entrepreneurial leadership roles.

In Latin America, scientific founders are commonly left to juggle multiple high-stakes roles at once: raising capital, taking products to international markets, and continuing to push technological frontiers. This is further rooted in the academic culture of many universities across the region, where entrepreneurship is still seen as a niche path rather than a viable or encouraged career option for scientific talent. As a result, the entrepreneurial potential of highly skilled scientists remains largely untapped.

Venture Building, also called a venture studio, is a model tailored to fit this gap. It is an institutional co-founder model that originates startups from scratch, not just accelerates existing ones. A venture builder scouts frontier science/IP, forms founding teams by pairing scientists with seasoned operators, structures the company (IP, governance, regulatory), provides shared product/BD resources, and co-invests to reach the first meaningful technical and commercial milestones. Unlike incubators/accelerators, venture builders are hands-on company creators with longer engagement, deeper ownership, and operational responsibility.

A venture builder scouts frontier science/IP, forms founding teams by pairing scientists with seasoned operators, structures the company, provides shared product/BD resources, and co-invests to reach the first meaningful milestones.

# Regional examples

GRIDX, the matchmaking model

GRIDX is a pioneering venture capital firm and company builder reshaping the Deep Tech and biotech landscape. With a science-first thesis, GRIDX has raised US$41.5 million across two funds and built a portfolio of 81 companies, 75% co-founded by women. These ventures span Argentina, Uruguay, Mexico, Colombia, Brazil, and Chile and collectively employ 1,000 people, including 700 scientists.

At the heart of the model is its matchmaking process: GRIDX identifies scientists with the drive to become entrepreneurs, recruits business professionals capable of executing in unfamiliar industries, and puts each pair through a three-month trial phase. After mapping hundreds of projects and co-founding six initial ventures, GRIDX raised a US$1 million prototype fund in 2016, a US$10 million Fund I, and, with IDB Lab as a limited partner in 2022, an additional US$30 million Fund II. Its companies have raised over US$100 million from international investors and achieved a first exit.

Vesper, co-founding with scientists

Vesper Ventures is a Brazilian venture builder focused on transforming high-impact scientific research into globally scalable startups. Unlike traditional VCs, Vesper partners with scientists at the earliest stages, often before a company even exists, directly engaging with universities to identify promising talent and breakthrough ideas.

The numbers are eloquent: after evaluating approximately 4,500 scientific projects, Vesper chose to co-found 8 companies. These ventures collectively hold 16 patents, have raised over US$30 million, and bring together a team of more than 50 PhDs.

Odisea, from education to investment

Odisea Labs is a LATAM-based innovation lab focused on advancing AI and Cryptography that integrates education, company building, and capital deployment under one roof. Founded in 2021, Odisea’s thesis starts one step earlier than typical venture builders: through NÚCLEO, its flagship technical academy, Odisea trains talent in applied AI and cryptography, including non-experts and candidates from nontraditional academic paths.

Odisea Labs runs incubation and accelerator programs that give NÚCLEO graduates a fast track into entrepreneurship. To date, Odisea has worked with 100 teams at the AI–cryptography intersection; collectively they have raised over USD 100 million from leading cryptography and AI investors. Odisea is finalizing its first venture fund, creating a continuous "learn–build–invest" flywheel designed to retain talent and compress the time from frontier research to market.

One key element missing is a concrete track record that shows Latin American companies have global reach and impact. Track records are super important for investors. While there are isolated examples, the overall image and history of successful exits in the region remain limited.

Roundtable participant

# Recommendations: Train, Fund, Validate

Stakeholders recommend starting with the basics: normalize entrepreneurship inside universities and top labs. Make it routine, run short, hands-on founder bootcamps and add recurring entrepreneurship modules to graduate programs, with mentors who can pair scientists with operators. Provide universities with the right incentives to engage with company building, circulating economic value back to the institutions.

A parallel demand emerged for increased non-dilutive capital in the initial stages. Stakeholders consistently requested small grants and rapid bridge funding to support proof-of-concepts before Series A, without this early funding, there will be no credible projects for subsequent financing. Finally, connect venture builders with VCs and corporates to secure funding for clinical trials, pilots, and initial market entry. Establishing dedicated corporate pilot lanes (at least one per hub) would enable product validation in real-world environments, and shared diligence and data-room templates would accelerate the most promising projects.

12 / 29 2 min

Metrics & Success Stories: Deep Tech KPI Frameworks

Recommendation 02 · Market Readiness

p. 58

In the process of fundraising and building investor confidence, clear, tailored metrics and compelling success stories are essential tools for Deep Tech startups. Unlike software ventures, where traction is measured by user growth, churn, or recurring revenue, Deep Tech operates on fundamentally different timelines and value drivers.

One of the key hurdles startups face is the lack of standardized, relevant metrics. Applying the same indicators used in traditional tech sectors often leads to misunderstandings and undervaluation. Metrics must be contextualized to each vertical, a biotech startup needs different benchmarks than one focused on quantum computing or advanced materials, and even within biotech, indicators should vary across sub-segments.

One key element missing is a concrete track record that shows Latin American companies have global reach and impact. Track records are super important for investors. While there are isolated examples, the overall image and history of successful exits in the region remain limited.

LADP investors roundtable participant

# Recommendations: Deep Tech KPI framework

The main pillar for this endeavor is robust data. We recommend establishing a LATAM Deep-Tech KPI framework to close the gap left by U.S. and EU-centric benchmarks and to improve the transparency and comparability of investment opportunities across the region. This report offers a first pass; moving from map to machinery will require follow-on convenings, working groups of investors, founders, and technical experts, to validate gaps, agree on relevant sources, and set clear data-collection cadences.

The framework should combine a standardized, cross-vertical core with sector-specific annexes. The standardized core would track graduation rates from one funding round to the next, internal rate of return over defined time horizons, and the share and depth of active corporate venture capital participation. Sector annexes would then capture what general KPIs miss: clinical and regulatory milestones in biotech, certification and qualification cycles in hardware, or approvals and interconnection timelines in climate and energy.

This two-tier approach preserves comparability while capturing each vertical’s operational realities. For startups, it creates a credible, investor-ready narrative grounded in standardized metrics. For the broader ecosystem, it generates a stronger evidence base, producing the robust numbers and decision-grade insights needed to elevate the region’s standing in the global deep-tech landscape.

13 / 29 2 min

Showcase & Visibility: Educate Privately, Convene Publicly

Recommendation 03 · Market Readiness

p. 59

Robust data is the first step. Second, and maybe most important, is communicating it to the appropriate stakeholders at the appropriate time, publicly and privately.

Privately, it is essential to educate investors on the viability and strategic significance of Deep Tech, an area traditionally absent from their consideration, and more so around LATAM’s. This information gap also includes local, off-the-radar investors: regions like southern Argentina harbor considerable, long-accumulated wealth, often tied to oil, agriculture, and mining, yet many local capital stewards lack exposure to alternative asset classes such as startups and Deep Tech.

Publicly, a mosaic of initiatives, from podcasts and newsletters to demo days and national summits, works to spotlight deep-tech talent. Notable examples include EMERGE’s Deep Tech Summit in São Paulo (launched 2024); Impacto Deep Tech LATAM, co-hosted on Uruguay’s coast by CITES, Draper Cygnus, GRIDX, Air Capital VC, and The Ganesha Lab with IDB Lab support; Draper Cygnus Tech Week 2025 across the Southern Cone; GRIDX’s 2025 U.S. Biotech Roadshow; Alianza Deep Tech Colombia’s Genera Summit in Bogotá; and The Ganesha Lab’s BIGinBIO alongside CORFO’s Go Europe Connect.

These initiatives are genuine wins, yet as the ecosystem expands, efforts that run program-by-program and country-by-country can drift into duplication, thin signaling, and missed network effects for lack of a unifying architecture.

This education should not rely on theory alone. Real-world examples are essential: startups that have secured follow-on rounds, entered regulated markets, or translated scientific breakthroughs into commercial products serve as proof points that demystify the deep-tech journey.

# Recommendations: Educate Privately, Convene Publicly

On the private side, governments, corporations, and regional stakeholders can institute dedicated Deep Tech investor-education initiatives, formal and informal, that address capital requirements, R&D timelines, exit strategies, and sector-specific success metrics. By designing targeted programs for high-net-worth individuals, the region can cultivate a new class of angel investors.

Publicly, the goal is to convene a single flagship Deep-Tech forum, not a routine conference, but a marquee gathering that places Latin America squarely on the global investment map. A curated mix of exhibitions, keynote sessions, and investor roadshows would showcase the region’s strengths, while an intentional invitation strategy ensures the room includes international LPs and strategic corporations. Coordinated under a shared strategy, today’s scattered sparks would cohere into a region-wide beacon.

14 / 29 1 min

Impact-Driven Narratives: Deep Tech for SDGs

Recommendation 04 · Market Readiness

p. 61

Once Deep Tech startups have aligned scientific innovation with business structure and begin fundraising beyond initial grants, a critical next step is to strategically reframe how they present their value. Participants repeatedly emphasized moving beyond a purely technical narrative, focused on scientific complexity or engineering novelty, toward a more impactful and globally relevant story.

This shift involves positioning Deep Tech as a vehicle for addressing the most pressing global challenges: climate change, the energy transition, and public health. As Cristián Hernández, general manager at Zentynel and author of Catalysts of Change, argues, the savviest biotech investors don’t merely analyse spreadsheets; they buy into stories.

Facts alone don’t move hearts, or wallets. Investors, regulators, and partners must not only understand the science but also feel the urgency and potential impact of what a company is building.

Cristián Hernández General Manager, Zentynel

That said, Deep Tech investment isn’t merely philanthropy. Participants emphasized that Deep Tech can deliver substantial ROI, with long-term value stemming from its capacity to resolve significant challenges while generating returns. Many investors are drawn to this hybrid appeal, they want more than just financial gain, but are not willing to compromise on performance. Deep Tech, when framed correctly, offers both.

# Recommendations: Deep Tech for SDGs

From the outset, think beyond technology and pure investment. Deep Tech can directly address climate change, inequality, and multiple SDGs. We recommend situating engineering and go-to-market strengths within clear societal outcomes, without slipping into greenwashing. Institutionally, the 2025 UNDP report Global Deep Tech Ecosystems opens with "Why Deep Tech Matters for the Sustainable Development Goals," including case studies on solid-state battery technologies. We recommend using these frameworks when pitching and when designing institutional approaches. As the agenda gains legitimacy, startups can leverage their mission as a strategic asset that differentiates them and attracts long-term partners.

15 / 29 2 min

Global Mindset: Language First, Structure Next

Recommendation 05 · Market Readiness

p. 62

For Deep Tech startups in Latin America, adopting a global mindset from day one is not just an advantage, it’s a necessity. While the region holds immense scientific talent, local markets are simply not large or stable enough to support the scale that breakthrough ventures require.

Whether due to limited ambition or barriers such as language, particularly difficulties with English, many founders still build with a local frame of reference. There needs to be a fundamental shift: startups must be designed with global relevance from the outset. Yet mindset alone is not sufficient. Operational readiness must go hand in hand with global thinking, aligning company structures with international standards to attract foreign capital and strategic partners.

Operational readiness must go hand in hand with global thinking. This means aligning company structures with international standards to attract foreign capital and strategic partners.

# Recommendations: Language First, Structure Next

Start with the basics. Make English the working language for internal and external materials, pitch decks, data rooms, technical docs, and contracts. Pair this with targeted English for Speakers of Other Languages (ESOL) upskilling for founders and research teams, focusing on the vocabulary they’ll use: IP and licensing terms, term sheets, regulatory and clinical/device documentation, and investor pitching. Provide operational support such as English-ready data-room templates, bilingual model contracts, and translation stipends.

Once those fundamentals are in place, layer in structural elements that signal global readiness: setting up holding companies in jurisdictions like Delaware, favored by international investors for its robust legal framework and transparent corporate governance. Register intellectual property early with the USPTO, it is often recommended to patent in the U.S. before filing in home countries. Another route is the Patent Cooperation Treaty (PCT): a single application recognized by 158 member states lets founders "time-buy" to nationalize filings across jurisdictions. Unfortunately, only 14 of 33 LATAM countries are registered, Uruguay being the latest signatory.

Together, these practices demonstrate that a startup is not only building cutting-edge technology but also structuring itself to operate and thrive on a global stage.

16 / 29 2 min

R&D Skepticism: Regional International Scientific Advisory Boards

Recommendation 06 · Investor Readiness

p. 65

Among the chief pain points identified were skepticism toward LATAM’s R&D capabilities and a fragmented regulatory landscape. Deep Tech companies rely extensively on R&D at top-tier academic institutions; their defining characteristic is that they emerge after years of rigorous research by individual scientists or teams of PhDs.

This process involves developing robust intellectual property and a lengthy, strategic technology transfer from academia to the commercial sector. The entire journey, from research and prototyping through development, validation, and commercialization, takes 25–40% longer to translate into returns than a conventional software company, according to Boston Consulting Group estimates. But before commercialization, the primary risk at early stages is the robustness of the underlying science.

Latin American ventures often face skepticism from international investors regarding the robustness and credibility of their early-stage scientific research.

U.S. investors, accustomed to evaluating founders and technologies emerging from prestigious institutions like Stanford, MIT, and Harvard, might doubt the credibility of innovations presented by founders from lesser-known universities in LatAm. This skepticism forces founders to undertake the additional challenge of proving the reliability of their technology and data.

Garret Dempsey Global investor, 2024

Consequently, this skepticism often results in an extended deliberation process for international investors, sometimes even perceived as biased, at a crucial stage in company development.

# Recommendation: Regional International Scientific Advisory Boards

To enhance credibility and accelerate investment decisions, we recommend establishing Regional International Scientific Advisory Boards within each major vertical. These impartial, high-caliber validation panels would combine global expertise, senior scientists and technology-transfer officers at institutions such as MIT, Stanford, ETH Zurich and Cambridge, with the local insight of distinguished LATAM researchers who have proven commercialization track records.

To ground the boards in excellence, they should include leaders from Latin America’s top patent-producing academic institutions: Universidade de São Paulo (USP), Universidade Estadual de Campinas (Unicamp), and Universidade Federal de Minas Gerais (UFMG) in Brazil; Universidad Nacional Autónoma de México (UNAM) and Instituto Politécnico Nacional (IPN) in Mexico; Pontificia Universidad Católica de Chile and Universidad de Concepción in Chile; Universidad de los Andes in Colombia; and CONICET in Argentina, among the top 20 LATAM patent filers over the past two decades.

These boards could conduct rigorous peer reviews of early-stage ventures at Technology Readiness Levels (TRL) 3–5, evaluating experimental design, reproducibility and IP robustness. Ventures that meet these benchmarks could receive a formal endorsement seal for investor materials, alongside tailored expert and policy support. Finally, the boards could publish an annual "State of Deep Tech Science" briefing highlighting validated breakthroughs and de-risked technologies.

Depending on needs, the boards could be housed (1) within a multilateral institution such as the IDB; (2) in an intergovernmental academic body like the Inter-American Institute for Global Change Research; (3) under a consortium of leading LATAM academic institutions; or (4) within a newly established, neutral committee run by an ecosystem enabler such as the LADP or the proposed Regional Deep Tech Coalition. The financing architecture could mix public–private partnerships, multilateral and philanthropic grants, and program-tied corporate sponsorships, with a package that balances financial honoraria and non-financial incentives to preserve independence.

17 / 29 2 min

Uneven Clinical Trials: Alignment Through Interoperability

Recommendation 07 · Investor Readiness

p. 68

LATAM does not have a centralized regulatory agency overseeing trial phases and market readiness for emerging biotech or AgTech innovations. Each country operates under its own rules and timelines, making navigation both challenging and essential for success.

As detailed by Cristián Hernández, Zentynel’s General Partner, a drug approval in Chile can take 6 to 8 months, in contrast to the 1.5 to 2 years it may take the Brazilian, Mexican or Colombian equivalents. Below is an overview of the regulatory framework different countries maintain for biotech.

Biotech regulatory review times by country
Country · AgencyReview timeNotes
Brazil · ANVISA18–24 months historicallyReforms aim for 120–365 days for innovative therapies, but separate GMP certification can add months.
Mexico · COFEPRIS5–60 days (equivalence route)Officially fast, yet backlogs often extend approvals to 1–2 years, prompting some firms to seek legal remedies.
Colombia · INVIMA12–18 monthsFlexible use of foreign data and SME incentives ease entry for companies with US/EU dossiers.
Chile · ISP6–8 months, predictableSmaller market but a transparent, strategic first stop for biologics, diagnostics, and precision medicine.
Argentina · ANMAT≤70 business days (from ~160 since 2017)Incomplete documentation can still cause delays.

For international investors, this augments the risk of investing, as it may not be strategic to back an early-stage startup that only complies with regulations of a single country, thus impeding regional and global expansion.

# Recommendations: Global-First Alignment Through Interoperability

To bypass this hurdle, regional investors have been encouraging portfolio startups to work with a global-first approach from the beginning, like the FDA or EMA, to immediately meet international standards. By aligning with FDA frameworks, companies signal adherence to rigorous standards, reducing perceived risks and facilitating smoother market entry.

However, stakeholders cautioned that an FDA-only posture can backfire, slowing iteration velocity, entrenching incumbent advantages, and imposing prohibitive compliance costs on early-stage ventures. Another model worth exploring is Próspera in Honduras, a Special Economic Zone offering bespoke regulatory pathways for health and biotech. Próspera self-reports "15× faster commercialization of drugs" and markets its health regime as enabling companies to go "10–100× faster." Under this framework, the gene-therapy startup Minicircle has conducted Phase I human trials.

That said, the model is contested, by bioethicists and biotech operators concerned about oversight, by Honduran authorities challenging Próspera’s legality, and by local communities. The zone is embroiled in legal disputes with the state amid efforts to unwind the SEZ framework. These tensions underscore both the potential speed advantages and the governance risks of using special-jurisdiction routes for biomedical development.

18 / 29 3 min

Regulatory Portability: The 34th Regime

Recommendation 08 · Investor Readiness

p. 70

Latin America’s Deep-Tech policy landscape is a patchwork: several countries have strategies and tech-transfer programs, yet startups still face duplicative approvals, uneven incentives, and slow, case-by-case rulemaking across borders. Investors and founders stressed that one missing layer is coordination, portable rules and institutional capacity that let a company scale regionally under one predictable framework.

Building on the prior chapter’s case for regional interoperability, this section outlines how mutual recognition, regional sandboxes, and a voluntary LATAM "single-startup status" could translate policy intent into cross-border scale, inspired by Europe’s emerging "28th Regime" model. A region-wide framework can sound politically unrealistic given sovereignty concerns and market fragmentation, yet a voluntary, modular design may reduce sovereignty costs, allow phased adoption, and create incentives for convergence.

There is international precedent to devise LATAM’s "34th Regime": a Pan-LATAM initiative to unite its 33 countries under a single regulatory framework for Deep Tech advancement. In December 2024 the grassroots coalition EU-Inc submitted more than 13,000 signatures urging the next European Commission to create a "28th Regime", an optional, pan-European company form that would let a startup incorporated in one member state operate everywhere else through one fully digital registry. The idea has won backing from founders of Stripe, Wise and Bolt, VCs like Index and Sequoia, and even Commission President Ursula von der Leyen.

France Digitale’s accompanying non-paper fleshes out the concept: a regulation (not a directive) establishing an online-first, mobile-first, API-first corporate status with minimal share-capital requirements, a single employee-stock-option regime, and due-diligence processes completed 100% online. By stripping away the "27 different hurdles" that slow cross-border expansion, the 28th Regime aims to give European scale-ups a clear path to become global champions. Particularly for Deep Tech, it proposes an explicit exemption from state-aid restrictions, recognizing that university spin-outs and science-heavy scale-ups may need five, ten or even fifteen years to break even.

While a region-wide "single startup status" is still some way off, a promising basic recognition stack is already taking shape. At the base, cross-border digital identity and electronic signatures are moving from pilots to practice, most visibly with Mercosur’s Digital Citizen. In trade, the new mutual recognition between Mercosur and Pacific Alliance "Authorized Economic Operator" programs, signed in 2025, streamlines supply chains without creating a supranational authority. In health, the Pan American drug-regulatory network and the single-audit program for medical devices offer workable reliance models. Taken together, this is recognition without harmonization, the scaffolding for a voluntary pilot of a regional Deep Tech startup label and shared sandboxes.

Down the line, the 34th Regime should also propose policies that tackle the lack of incentives for Deep Tech ventures, from programs to create Deep Tech companies to public-purchase mechanisms and tailored regulations, as identified by ECLAC in 2020. Rather than an exhaustive list, the following highlights a diverse set of innovative regulatory strategies that governments in the region are already implementing, which could serve as primers for the 34th Regime.

Country primers for the 34th Regime
CountryInitiativeWhat it does
ChileDirectory of Deep-Tech Startups (2022; update 2024)The Education Ministry mapped 300 startups (44% biology, 43% digital) with high R&D intensity; a 2024 follow-on further characterized Chile’s Deep-Tech base.,
ChileTechnology Transfer Bill (2024)Draft law to boost university-to-industry transfer via stronger IP rules and hubs, shared labs, incubators, and accelerators.
ColombiaSpin-off Law (2017)Enables researchers at public universities to found companies from their science, clarifying dual-remuneration rules.
ColombiaPatent Push (2021–2022)Science Ministry programs doubled patent applications and placed Colombia 3rd in LATAM for filings in 2022.
ArgentinaCONICET Rules (2019)Reforms allow researchers up to a two-year leave to create technology-based enterprises.
ArgentinaEntrepreneurship Law & FONDCE (2017)Streamlined startup formation and launched a matching-funds program, instrumental for backing ~79% of local deep-tech startups.
19 / 29 4 min

Public Investment: Grants, Matching Funds & the Israeli Model

Anchoring public R&D

p. 73

Public funding plays an essential role in the development of Deep Tech ecosystems, particularly during the early stages of R&D. Over the past decade, Chile, Brazil, Uruguay, Argentina, and Colombia have introduced public programs, from patent drives to millions of dollars in annual matching funds, to foster technology-based entrepreneurship.

Such support mechanisms have proven vital in bridging the financing gap, allowing startups to advance from early R&D to market entry without heavy equity dilution. Public funding programs accounted for 70% of all deep-tech financing in Brazil, as noted by EMERGE in 2024. Governments increasingly recognize that Deep Tech startups are a vital component of national competitiveness, witness Costa Rica’s semiconductor roadmap to attract FDI (2024) and Chile’s roadmap to advance its quantum technology sector.

Governments have increasingly recognized that Deep Tech startups are not just about fostering innovation, they are also a vital component of national competitiveness.

However, this heavy reliance on public programs signals an imbalance that could hinder long-term ecosystem maturity. In the US, EU and OECD, businesses supply over 60% of R&D funding (nearly 80% in China) while government shares hover around 20–30%. In LATAM, by contrast, the state underwrites roughly 60% of R&D, far above its peers, whereas private investors contribute only about 35%.

Public financing typically manifests in two forms. First, non-dilutive grants, which preserve equity for founders and early investors while enhancing capital efficiency, especially important because Deep Tech projects often require prolonged research before a viable product emerges. Second, matching-fund programs. Inspired by the Israeli model, governments in Argentina and Uruguay have implemented matching-fund initiatives that co-invest with private venture capital and angel investors, reducing risk for private investors and creating a multiplier effect.

Is the challenge one of increasing the amount of funding, or is it about improving the quality and efficiency of the available resources?

A question raised in the research

The public sector’s core role should be to complement and de-risk private deep-tech investment through targeted programs, matching-fund schemes, special economic zones, shared labs and applied R&D grants, while advancing the regulatory framework via technology-transfer laws, empowered economic-development corporations, STEM education, and streamlined permitting. Although Latin America already hosts promising examples in Chile, Argentina, Brazil and beyond, these instruments remain too fragmented and limited in scale. Weaving them into a coherent, region-wide playbook will be essential.

# The case of biotech in Brazil: broad but shallow public funding

The biotech sector in Brazil stands out as one of the most mature Deep Tech ecosystems in the region, representing almost 60% of biotech startups across Latin America. Public funding programs such as PIPE FAPESP and FINEP have been instrumental. However, participants pointed out that grants still tend to be "low-ticket funding," insufficient to fully meet the substantial R&D and laboratory setup needs essential for scaling. Rather than increasing the number of funding rounds, Brazilian investors suggested increasing the funding amounts per round.

FAPESP
A leading state-level funding agency, central to supporting both fundamental research and innovation through academia-company collaborations.
PIPE Program
Inspired by the U.S. SBIR model, funds innovative R&D in small companies based in São Paulo.
Cooperative Research for Innovation
Fosters structured partnerships between universities and companies, with programs on AI, advanced mobility and biotech alongside Shell, IBM and GSK.
International Research Centers
In March 2025, FAPESP launched a R$5 million initiative to boost São Paulo’s Deep Tech competitiveness, focusing initially on a biology center for immune and inflammatory responses.
FINEP
Linked to the Ministry of Science, Technology, and Innovation (MCTI), FINEP is Brazil’s main federal-level financier of business R&D and innovation.
Mais Inovação Program
Launched in 2024, a flagship federal program offering non-reimbursable grants and credit for R&D-intensive companies in health, energy, ICTs, and sustainability.
Private R&D Center Attraction Incentives
In partnership with BNDES, FINEP is offering US$500 million to incentivize multinational and national firms to set up R&D hubs in Brazil.

# Matching funds in Argentina, Chile & Uruguay

Matching-fund schemes address the well-known market failure of private underinvestment in innovation by co-investing public capital alongside private resources, typically covering 40–60% of eligible costs on the condition that private partners supply the remainder. This structure aligns incentives, enforces rigorous project validation, and creates a self-sustaining cycle.

Israel’s resurgence from the mid-1980s crisis owes much to three flagship programs. The 1985 R&D Law reimbursed up to 50% of corporate R&D, lifting private R&D spending to 4% of GDP. The 1991 Incubator Program leveraged US$600 million to underwrite 24 private incubators, fueling 1,700 startups. The 1993 Yozma Program injected US$100 million into ten VC funds (40% public, 60% private), sparking a domestic venture industry that now manages over US$10 billion and has generated more than US$80 billion in value creation.

Israel’s playbook is an extension of its security doctrine: mandatory service in elite IDF tech units, especially 8200 and 81, funnels thousands of engineers into the civilian economy; Unit 8200 alumni alone have launched 1,000-plus startups., In the Latin American context, a comparable large-scale public–private mobilization would require different rationales aligned with domestic strengths, natural-resource-based innovation, climate adaptation, biodiversity protection, public health, biosecurity, or logistics.

Argentina, FONDCE (2017)
Inspired by Israel, Argentina’s Entrepreneurs Law established FONDCE ("Fund of Funds") to underwrite science-based accelerators and early-stage VCs, and simplified company formation to under 24 hours. Within two years, five FONDCE-backed accelerators had invested in 79% of Argentina’s investor-funded Deep Tech ventures. Alumni include NotCo and Autofact.
Chile, CORFO (since the early 1990s)
Through FONTEC (now under the Innova umbrella), CORFO provides reimbursable grants covering 40–65% of private R&D costs. The FONDEF fund co-finances pre-competitive joint R&D between academia and firms.
Uruguay, Law 20.075 & the Innovation Hub
Uruguay enacted Law 20.075 (2022, approved 2023) to kick-start Deep Tech ventures, and in May 2024 inaugurated the Uruguay Innovation Hub (UIH) with US$10 million for a 1:1 matching-funds program.,
20 / 29 4 min

Pensions: A Fund-of-Funds for Domestic Deep Tech

Recommendation 12 · Regional Coalition

p. 79

Pension funds should be part of the conversation on Deep Tech financing in Latin America. They are among the region’s largest pools of patient capital, yet much of that capital is deployed abroad rather than into domestic innovation. Beyond isolated remarks in private interviews, we found no coordinated effort to bring pension trustees, supervisors, and Deep Tech managers around a shared investment architecture.

Global benchmarks clarify both feasibility and urgency. Across Europe and the United States, pension funds account for under 5% of the top-50 Deep Tech investors by deal count by 2024, well behind VC funds, government entities, and corporate VCs. Even so, their presence demonstrates an investable foothold. For the authors of the 2024 State of European Tech Report, redirecting even a small share of pension assets currently invested outside the EU could unlock the patient capital needed to seed and scale Deep Tech.

Corporates are leaning in
2.8×Overall corporate venturing growth
4.2×Corporate–deep tech collaborations
71%Of firms expect deep tech to grow in their portfolio

Global corporate venturing grew 2.8× and corporate–deep tech collaborations 4.2×; 71% of firms expect deep tech to weigh more in their portfolios.

As originally publishedAs of September 2025Report p.89

The figure as the report published it, September 2025.

SourceIESE Business School, Open Innovation: How Corporate Giants Can Better Collaborate with Deep-Tech Start-ups

Methodology: IESE 2021 (ledger #122). Multipliers over 2017–2021, not a time series. New context: LATAM CVC activity doubled 2020–2023 and AI is now the leading LATAM CVC theme (41% of funds), not in the report.

Distribution (%) of top-50 Deep Tech investors by deal count and investor type, 2015–2024YTD. Source: State of European Tech Report, Atomico.

The 2025 "CERN for AI" white paper, authored by the European Union, also points to European pensions to unlock patient capital. In the United Kingdom, the idea is entering the mainstream. Most importantly, the UK’s Mansion House policy reforms are already putting this approach into practice, and France’s Tibi initiative goes further by setting clear commitments for institutional investors. Under Tibi’s first phase (2020–2022), institutional investors committed €6.4 billion; its second phase projects €40–50 billion in technology funds under management by 2026.,

While precise figures are hard to aggregate across LATAM, a useful order-of-magnitude comes from the OECD: in Chile, Mexico, Brazil, Peru, and Uruguay, pension AUM total roughly US$1 trillion. Redirecting even 1% would mobilize USD 10 billion for domestic Deep Tech. This 1% would represent about four times the USD 2.5 billion deployed into LATAM Deep Tech since 2018, enough to turn today’s funding bottleneck into an investable pipeline.

# Recommendation: A Fund-of-Funds path for patient capital

A coalition-led strategy can change the frame: instead of treating pensions as distant spectators, invite them, prudently and voluntarily, into vehicles that channel a small share of assets toward local R&D and Deep Tech, without compromising fiduciary duty. Immediate priorities are to specify investable vehicles that fit fiduciary mandates, map the regulatory tweaks that would enable pilot allocations, and define safeguards that protect senior pension tranches.

Governments should take the lead by establishing a public-anchored Fund-of-Funds (FoF). By pooling public-sector balance sheets, including mutual insurance and pension funds, governments can set an example, then commit to independent managers through clear, competitive mandates, drawing inspiration from the 2018 Tibi report in France. The UK’s Mansion House Accord (May 2025) has taken this French policy as a first step, pledging to allocate 10% of pension portfolios to private markets by 2030, with at least 5% ring-fenced for UK assets. Complementing this, the BVCA’s 2025 expert panel proposes a UK "NOVA" program, modeled on Tibi, steps LATAM can mirror with development banks and multilaterals.

# Shared R&D infrastructure

From quantum rigs and petabyte-scale AI clusters to secure blockchain nodes and biotech wet-labs, Latin American innovators converge on one persistent bottleneck: the region’s limited supply of specialised, capital-intensive R&D infrastructure. Governments have begun to chip away at the gap: Brazil now boasts 11 active biotech hubs, Chile at least three, Uruguay at least seven, and Argentina at least one., Yet the region is still scratching the surface of what is needed.

Parque de Innovación de Buenos Aires (Argentina)
An urban innovation district spanning 12 city blocks and 340,000 m², uniting universities, research centers, co-working spaces, and startups.
StartupLab.01 (Chile)
CORFO and Fundación Chile launched a shared lab and cowork space for Deep Tech startups focused on climate tech, supported by the IDB and partnered with GRIDX.
Patagonia Biotech Hub (Chile)
A shared lab and cowork space for biotech startups, launched September 2024 with backing from the Ministry of Science.
CBT SOFOFA HUB (Chile)
The Translational Biotechnology Center accelerates adoption of biotechnology across biomedicine, mining, aquaculture, forestry, and agriculture.
New Lab (Uruguay)
Newlab’s first LATAM hub, a partnership with ANII, Globant, UPM and others, offers state-of-the-art prototyping labs and pilot testbeds inside Montevideo’s Innovation Campus.
21 / 29 4 min

Social Clusters: International Cohorts & Ecosystem-as-a-Service

Recommendation 10 · Investor Readiness

p. 82

Beyond capital, infrastructure and regulatory frameworks, Latin America’s Deep Tech transformation depends on systematically building social clusters, dense networks connecting researchers, entrepreneurs, investors, and institutions that enable knowledge transfer and risk mitigation at commercial scales. These networks form the invisible "relationship architecture" that converts research breakthroughs into scalable ventures; without them, even breakthrough innovations can remain trapped in laboratories.

# The network infrastructure gap

Scientific talent abundance means little without connection infrastructure. A study of Chilean biotech firms revealed that almost half of business links (47%) originated from personal connections. Analysis of global tech hubs shows serial entrepreneurs and investors serve as crucial "ecosystem connectors," with individual network brokers linked to up to 15 different ventures simultaneously.

Silicon Valley’s success stems partly from its 60+ annual tech conferences creating "temporary townships" of concentrated interaction, while Cambridge UK’s cluster generates £18 billion annually through systematic face-to-face networking., Israel’s ecosystem produces one startup for every 1,400 citizens largely because military-alumni networks create pre-established trust. Berlin adds another model: its rise was driven less by capital abundance than by grassroots density, 40,000 business registrations annually and hundreds of informal meetups, only after which capital followed, with Berlin startups raising over €10 billion in 2021, surpassing London.

Latin America has systematically underinvested in this relationship infrastructure. Past programs provided capital and services but failed to establish enduring networks, causing knowledge leakage and preventing ecosystem self-reinforcement.

# Contrasting network-formation models

Start-Up Chile (SUC), launched in 2010, is widely recognised as Latin America’s most successful public innovation initiative. It pioneered an "import and mingle" model, offering equity-free $40K grants plus one-year visas to foreign entrepreneurs who relocated to Santiago, and enforced mixed cohorts, a socio-psychological mechanism that encouraged interaction between Chilean and foreign teams. A 2014 study found the $40K grant was useful but non-differentiating; the real divergence was peer learning: only 16% of foreign founders named it their primary source of value versus 45% of domestic founders.

Lower-confidence entrepreneurs are more likely to observe, imitate, and internalize concrete behaviors modeled by credible peers, especially when reinforced in shared workspaces. SUC’s bet was that imported know-how could become shared know-how if you engineered the right social collisions. Results exceeded expectations: 3,000+ startups from 85 countries entered SUC, generated over $1 billion in collective sales and raised $1.2 billion in follow-on funding, while 68% of Chilean founders reported changing their financing strategies after engaging with international peers.

Colombia pursued systematic domestic network strengthening through the Alianza DeepTech Colombia, designed as a private Ecosystem-as-a-Service (EaaS) model. The Alianza united 31 stakeholders, universities, corporations, government agencies, under coordinated action commitments: joint research projects, cross-institutional mentorship, and unified policy advocacy. The 2024 DeepTech Colombia report documents 56% year-over-year growth in Deep Tech startups (now 56 active companies), 500+ new jobs, $60 million in fresh investment, and $800+ million in total ecosystem value, with near gender parity (49% female founders).,

# Value generation through networks

Across both models, the advantages of social clustering are clear and measurable. Dense networks create economic advantages through four primary mechanisms:

Accelerated knowledge spillovers
Technical insights flow faster through personal relationships than formal publications. Face-to-face interactions transfer tacit knowledge, equipment tricks, failure-pattern recognition, market-timing intuition, that never appears in academic papers.,
Risk mitigation
Trusted network referrals reduce investor due-diligence costs while improving deal quality. Informal information supplements formal due diligence.
Resource bundling efficiency
A startup needing specialized equipment, legal advice, and a pilot customer can often find all three through cluster connections, assembling domain experts, grant money, and partners much faster than starting cold.
Self-enforcing ecosystem loops
Each entrepreneurial success feeds back into the ecosystem, generating new social capital and nurturing talent. Over time, a culture of "giving back" takes root, an Ecosystem Nutrition Cycle where resources and experiences compound.

# Lessons for Latin America’s Deep Tech ecosystems

Experiences from Chile, Colombia, and global hubs underscore a common theme: ecosystems thrive where networks are deliberately built, continuously reinforced, and institutionally anchored. Three structural elements matter most:

Continuity and follow-through
Isolated interventions create sparks but rarely sustain momentum. Start-Up Chile successfully imported global know-how, but the absence of retention and institutional anchoring meant most of the value dissipated once participants left.
Domestic alliances
Durable ecosystems emerge when local actors coalesce around shared goals. Colombia’s Alianza DeepTech shows how universities, firms, and government agencies aligning under joint commitments and KPIs transformed a fragmented landscape into a nationally visible cluster.
The density dividend
Density, the frequency and intensity of interactions, drives innovation as decisively as funding. Capital must be complemented by recurring spaces of interaction that allow ideas, talent, and capital to circulate with speed and trust.

Durable ecosystems emerge when local actors coalesce around shared goals. Domestic alliances institutionalize trust, concentrate resources, and create the connective tissue that enables Deep Tech ventures to scale.

These lessons converge on a hybrid framework. First, prioritize continuity by embedding retention incentives, tracking mechanisms, and institutional anchors. Second, formalize domestic alliances that unite universities, corporations, investors, and government agencies. Third, cultivate density through recurring interaction platforms, monthly meetups, flagship summits, and sector-specific convenings, that replicate the "density dividend" of global hubs.

22 / 29 5 min

CVC: Matchmaking Bridges & Observatory

Recommendation 09 · Investor Readiness

p. 88

Corporate venture capital (CVC) has emerged as a linchpin for accelerating private-sector R&D. CVC refers specifically to corporate-backed VC arms using their own balance-sheet capital, distinct from traditional VC, which manages external LPs’ funds with a primary focus on financial returns.

While both carry the "venture capital" designation, they operate with distinct logics. Traditional VCs are primarily accountable to LPs for financial performance; CVCs pursue dual objectives, financial returns alongside strategic benefits such as access to emerging technologies, new markets, talent, and organizational learning. This makes CVC units the corporation’s "eyes and ears" in the external innovation ecosystem.

CVC sits within a wider corporate-venturing toolbox that includes incubators, accelerators, venture clienting, strategic partnerships, tech scouting and challenge prizes.

The most effective programs pair investment with privileged assets, distribution, data, domain experts, regulatory know-how, and facilities for pilots. CVC typically takes three main shapes: equity investments via dedicated corporate funds; R&D partnerships, where startups receive financing in exchange for co-developing new products; and licensing agreements that provide non-dilutive revenue while preserving startups’ core IP.

# Global benchmark

Globally, the trend is unmistakable. Major incumbents such as Pfizer, Ford, Tyson Foods, Lockheed Martin Ventures and GM are acquiring Deep Tech startups and spinning up their own venture arms. From 2017 to 2021, overall corporate venturing expanded 2.8×, corporate–Deep Tech collaborations surged 4.2×, and 71% of firms expected the weight of Deep Tech in their corporate-venturing portfolios to grow. Still, momentum is uneven: by 2021, about 90% of U.S. corporates operated venture arms; 57% of firms in East and Southeast Asia had launched CVC programs; and in Latin America, only ~40% of companies were engaged.

In Sweden, roughly 70% of local startups have secured investment from local corporate venture arms; CVCs participate in about 30% of Series A rounds and 60% of Series B rounds. European evidence points the same way: Hello Tomorrow finds lower bankruptcy rates for CVC-backed startups (~1.24%) vs. those without (~2.58%), suggesting corporate investors contribute more than capital, distribution, technical validation, and procurement pathways that improve survival odds.

# LATAM’s CVC reality check

Latin America reveals both immense potential and limitations. The region combines the weight of major local multinationals such as Cemex, Marcopolo, Grupo Bimbo, and JBS with global incumbents including Siemens, IBM, Nestlé, Pfizer, and Novartis. Local firms contribute market knowledge; international players bring advanced technologies and global networks. The broader CVC market across all sectors reached $3B in 2024, up from $1.5B in 2023.

Dealroom provides statistics specific to Deep Tech in the region: funding rose from $9M in 2020 to $119M in 2022, then retracted to $73.9M in 2023 and $36.5M in 2024, about 70% below the peak, yet still roughly 4× the 2020 baseline, suggesting a market recalibration after an overheated period. The region appears to have no shortage of interested corporations, but rather a deficit of dependable avenues.

Corporate VC into LATAM deep tech
USD millions
$0.0M$50.0M$100.0M$150.0M2020202220232024

Corporate venture capital into the region’s deep tech peaked at USD 119M in 2022, then cooled with the wider funding market. The base is set for the CVC Bridge the report proposes.

As originally publishedAs of 2024Report p.90

The figure as the report published it, September 2025.

SourceDealroom.co, Deep Tech Overview: Latin America

Methodology: Dealroom LATAM deep tech CVC (ledger #127). 2021 is "n/a" in the report (null). Fell 70% from the 2022 peak but still 4× the 2020 base, present the full series, not just the 4×. Needs 2025/H1-2026 extension.

CVC investment trend in LATAM’s Deep Tech (2020–2024). Source: Dealroom Global Tech Ecosystem Index.

# CVC–startup matchmaking

A new generation of accelerators, venture studios, and consultancies is professionalizing the matchmaking process between startups and corporations. Regional firms like 414 Capital, Pragmatec, Bluebox, New Venture Groups and New Genesis have incorporated corporate investment into their value propositions. These programs address a problem heavily reported by our stakeholders: an over-reliance on personal connections to secure investments. A neutral matchmaking program with transparent intake, common NDAs, shared data-room templates, and quarterly demo days can shift the model from relationship-only to evidence-driven.

For corporates entering Deep Tech CVC, pairing with SMEs can turn abstract science into operational proof quickly. SMEs are the backbone of Latin America’s economy, 99% of its firms and about two-thirds of the workforce. Their agility makes them a natural testbed for pilots in agriculture, Industry 4.0, and mobility. Industry 4.0 pilots have been shown to improve productivity by 10–30% and reduce waste or downtime.,

The Ganesha Lab

A LATAM biotech accelerator bridging the funding gap via education, mentorship, and market access, organizing international events and "small missions" to connect startups with global networks including early CVC access.

Startuplab.01

A public-private initiative based in Chile that catalyzes Deep Tech startups by providing cutting-edge laboratory infrastructure for entrepreneurs in biology and related fields, plus corporate connections.

Wayra Hispam

Operated by Telefónica’s innovation hub, Wayra Hispam co-invests alongside TheVentureCity, offering up to $250K per startup and facilitating corporate partnerships.

CMPC Venture Capital

The CVC arm of a Chilean multinational, investing in sustainable innovation and next-gen materials; it led a €4.8 million seed round for Strong by Form.

# Recommendations: A Deep-Tech CVC Bridge for LATAM

Latin America needs a neutral Deep-Tech CVC Bridge to close the gap between its most promising science-based startups and the global corporate funds that can propel them beyond Series A. A dedicated bridge, co-run by organisations like the LADP, leading accelerators and supported by a multilateral, would organise recurring virtual pitch days and cross-border roadshows, offer a standardised CVC-ready data-room template, and maintain an open database of corporate investors and their thematic priorities.

The Bridge can anchor a regional CVC × Deep Tech Observatory, filling key data gaps: CVC participation, survival/attrition, time-to-next-round, procurement conversion, plus a LATAM benchmark of bankruptcy rates with vs. without CVC support. By releasing open, anonymized dashboards through standardized reporting, the Observatory can shift the market from relationship-driven to evidence-driven. For corporates, CVC programs should target SME clusters, keep pilots small-scope and short (8–12 weeks), and focus on one clear KPI, with public co-funding from national or IDB/CAF programs to lower costs.

23 / 29 4 min

How SEZs 4.0 Convert the LATAM Discount into a Defensible Edge

Said Saillant, PhD, Founder, Societas Sapiens

p. 94

Special Economic Zones (SEZs) in Latin America have proven they can attract global tech leaders. But traditional SEZs rely on tax incentives, a race to the bottom that competitors can match. The breakthrough lies in Calibrated Regulatory Autonomy (CRA): giving SEZ authorities the power to adapt regulations in real-time while maintaining democratic oversight.

UNCTAD defines SEZs as geographically delimited areas where governments offer a tailored regime, streamlined regulation, targeted fiscal incentives, and dedicated infrastructure, to de-risk investment. They are not fringe experiments: UNCTAD counts 5,383 SEZs across 147 economies, with China alone hosting more than half. Its flagship zone, Shenzhen, transformed from a fishing village into a US$510 billion tech hub generating over 11 million jobs and contributing roughly 3% of China’s GDP.

# From tax perks to time advantage: Calibrated Autonomy

Calibrated Regulatory Autonomy (CRA) means a statutory delegation that lets a zone steward modify, waive, or pilot regulatory requirements within strict guardrails. The law sets scope, non-retroactivity, transparency, service-level deadlines, appeals, and sunset or renewal. The steward issues time-boxed permissions, gathers evidence, and graduates proven conditions into standing rules mapped to external standards.

Proven track record

Costa Rica attracted Intel’s $1.2B+ expansion, creating 3,400+ high-skill jobs and drawing Databricks. The Free Trade Zone regime now contributes ~15% of GDP through 265,000 jobs, returning nearly $3 for every $1 in tax expenditure. The Dominican Republic operates 87 Free Zones hosting 25+ electronics leaders including Eaton and Rockwell Automation, generating $8.1B in exports and 197,600 direct jobs. Uruguay leveraged its stable democracy to attract Satellogic’s manufacturing operations and Newlab’s innovation hub; twelve Free Zones support 64,000 direct jobs and achieved near-record exports in 2024. These successes share a pattern: they moved beyond simple tax incentives to create predictable, adaptive regulatory environments.

Table 1. SEZs in practice, CRA in contrast
DimensionTypical LATAM SEZCRA-SEZ (upgrade)
GovernanceNational Free Zone law grants fixed incentives; many ministries handle permits; no single front doorOne steward runs intake, triage, and a single appeals path under statute
ApprovalsPaper shuttling; ad hoc committees; timelines swing with electionsClocked service targets per step; inquiry→pilot ≤30 days for low/medium risk
Rule changeDecrees update rules infrequently; firms wait quarters/yearsTime-boxed, conditional permissions; scheduled "graduation" into SOPs
StabilityClauses cover taxes/customs only; little on data, AI, pilotsNon-retroactivity, stability agreements, published memos cover novel uses
ComplianceGeneral regulators apply one-size rules; no risk tiers; no pilotsTiered evidence (test plans, monitoring, power limits); renewals depend on outcomes
TransparencySparse metrics; few written precedents; broker folkloreLive dashboards, decision memos, searchable precedent library
Standards mappingPatchy FDA/EMA/ISO alignment; exporters redo tests abroadIn-zone conformity assessment mapped to US/EU/ISO for portability
TalentInstitutes sit outside; curricula lag vacancies; weak apprenticeshipsInstitutes co-locate; curriculum co-design; SLAs for apprenticeships; payroll-levy co-funding
Capital accessSlow procurement; episodic CVC; nonstandard dataroomsStandard datarooms, vendor whitelists, recurring roadshows; faster onboarding
DisputesLocal courts/generic arbitration; long resolution timesModel contracts, named venues; target ≤90-day resolution

Source: Composite; see report footnote 126 for jurisdictional sources.

Baseline SEZs trade taxes for factories. CRA trades predictable speed and precedent for durable Deep Tech investment, which removes the priced-in LATAM discount.

# The democratic regulatory sweet spot

A LATAM SEZ with CRA pairs democratic legitimacy, contractual stability, and rapid adaptation, so it outperforms Gulf, US/EU/UK, China, and Hong Kong models on innovation velocity at lower risk.

Jurisdictional benchmark
JurisdictionCore limitationBusiness impactLATAM SEZ + CRA advantage
Gulf StatesPolicy by executive decreeSovereign/data appropriation riskConstitutional protections + rapid adaptation
US/EU/UKMulti-layered complianceSlow, expensive approvalsStreamlined processes + global portability
ChinaTechnology-transfer mandatesClosed innovation ecosystemOpen integration with global partners
Hong KongGeopolitical constraintsShrinking policy autonomyFresh mandates + design flexibility

# Talent infrastructure that scales

Place training institutes inside the SEZ to lock strategic partnerships with anchor firms and the zone steward. That placement enables curriculum co-design for live vacancies, shared labs with duty-free gear, guaranteed apprenticeships, payroll-levy co-funding, fast instructor visas, and direct placement pipelines into tenants.

INFOTEP, Dominican Republic
A 1% payroll levy finances custom tech courses co-designed with Free Zone tenants and delivered on-site; programs retool quickly for new lines.
INA, Costa Rica
Free, skills-based training in high-demand sectors; dual vocational tracks modeled on Germany’s system expand firm-aligned talent.
INEFOP, Uruguay
With Uruguay XXI, "Finishing Schools" co-finance up to 70% of bespoke company training plans to ramp workforces for new investments.

# Geopolitical positioning: SEZ-first, ADD/CHIPS as levers

SEZs anchor nearshoring, they deliver predictable rules, fast permits, and bonded logistics. The Alliance for Development in Democracy (ADD) and the CHIPS Act’s International Technology Security and Innovation (ITSI) Fund play supporting roles that amplify the zone’s pull. ADD provides a diplomatic umbrella for joint statements and supply-chain cooperation; CHIPS/ITSI provides grants and technical assistance for trusted semiconductor supply chains, co-financing Assembly-Testing-Packaging (ATP) lines and workforce programs inside the SEZ.

# The compounding advantage

Traditional SEZs handle place and logistics. CRA attacks time. In Deep Tech, time gains snowball: early regulatory clarity shortens build cycles, pulls stronger talent, and converts each pilot into reusable playbooks. SEZs lay the platform; CRA supplies pace and credibility. Together they turn chronic disadvantages into a durable moat.

Latin America transforms from a discount destination into a premium platform for global innovation, one competitors cannot easily copy, because the advantage lies not in any single policy but in the compounding returns of adaptive, democratic governance.

24 / 29 3 min

Why Latin America is a Lab for the New World Order

The New Battlefronts of Tech

p. 98

World politics is tending towards a paradox. Geopolitics is restoring Cold War dynamics, with states seeking technological autonomy that guarantees superiority over adversaries. However, national governments have scarcer means and more dependencies, on each other and on new actors such as technological multinationals. "No country alone can make an iPhone today," as economist Eric Beinhocker aptly puts it.

The return of spheres of influence is taking place in a world of hardwired networks, where old alliances have become less certain, with the United States taking distance from NATO. This combination is creating new battlefronts for critical technologies, where large and small countries play a new game of appropriation versus autonomy. Many Latin American countries hold an indispensable supply of resources for Deep Tech, from raw materials to energy, yet have had, so far, wasteful institutions and disjointed ecosystems, lending themselves mostly to appropriation.

Now that there is less West and more Rest in geopolitics, how will resource-rich places like LATAM realign to the emerging world dis-order?

# The politics of appropriation in a networked world

In 1945, Vannevar Bush published Science: The Endless Frontier, advocating that the United States invest in what today we would call Deep Tech, to engineer advantages in knowledge into economic and military competitiveness. Eighty years later, Bush’s predictions have become the doctrines of states, from the US to China. Today, geopolitical preparedness is technological preparedness, and vice versa. We are back to the ’60s: competition between states plays out at the technological frontier, ranging from Artificial Intelligence to Quantum Technologies to Biotechnologies. Every investment in inventions is a dual-use investment in a world where alliances are more fragile and conflicts more frequent.

A nation which depends upon others for its new basic scientific knowledge will be slow in its industrial progress and weak in its competitive position in world trade, regardless of its mechanical skill.

Vannevar Bush Science: The Endless Frontier (1945)

The Biden administration had started imposing export controls on critical technologies and offering incentives through the Inflation Reduction Act. In 2022, TSMC received $6.6 billion in direct funding and $5 billion in low-cost loans through the CHIPS Act to build a foundry in Arizona; it later announced an additional $100 billion investment. Today, the United States, China, the European Union and others are trying to repatriate these capabilities, or appropriate them, evident in the Trump Administration’s use of tariffs to coerce adversaries and allies alike into buying or becoming Made in the USA.

Today, geopolitical preparedness is technological preparedness, and vice versa. Every investment in inventions is a dual-use investment in a world where alliances are more fragile and conflicts more frequent.

As for China, they understood early that geography is destiny. Part of China’s National Development and Reform Commission 2024 directives include a strategic positioning of their Deep Tech industries, framed as a response to "a shift in the international balance of power, the rise of the East and a relative decline of the West." China has been building a network of Silk Roads worldwide, where the silk is the natural resources and minerals quintessential to building new tech. As Ángel Melguizo and Margaret Myers put it, many of China’s ICT and high-end manufacturing companies have sought to engage more extensively with Latin America and the Global South. If the iPhone cannot come to China, then China goes to the iPhones.

25 / 29 5 min

China’s Deep Tech Plans

p. 101

China has woven Deep Technology into the fabric of its long-term development model, positioning it as a pillar of an innovation-driven, self-reliant economy. While the release of DeepSeek looked like an overnight sensation, it was anything but.

Deep Tech, aka "New Infrastructure" in China, sits at the heart of the country’s strategy for sustainable, innovation-led growth. The 14th Five-Year Plan (2021–2025) spells out an extensive support system, while the 2021 Science and Technology Progress Law reaffirms Beijing’s determination to keep pushing frontier research. The Ministry of Industry and Information Technology, with six other ministries, has spotlighted a roster of "future industries" (quantum computing, 6G, space technologies, next-generation materials) as pillars of China’s new "quality productive forces."

A flagship element is the "20 + 8" cluster agenda, which earmarks twenty strategic emerging industries and eight forward-looking fields, biotechnology, next-generation ICT, advanced manufacturing, and more, and bundles them into regional hubs where companies, research institutes and investors collaborate at scale. In November 2022 the Ministries of Science & Technology and Education green-lit ten pilot "future industry" parks across eight provinces and municipalities, each combining co-creation spaces, incubators, accelerators and industrial parks, underpinned by a 30-point talent scheme.,

Between 2017 and 2022, Deep Tech’s share of total domestic tech investment jumped from 15% to 71%, reflecting how quickly capital has followed this coordinated policy drive.

What a coordinated push looks like
15%of tech investment in 2017
71%by 2022
$138Bstate-backed deep tech fund (2025)

China shows the other end of the spectrum: deep tech leapt from 15% to 71% of domestic tech investment in five years, backed by a USD 138bn state fund.

As originally publishedAs of 2022Report p.101

The figure as the report published it, September 2025.

SourcesGlobal Private Capital Association (GPCA), 2023 Emerging Trends in Asia; The Quantum Insider, China Launches $138 Billion Government-Backed Venture Fund, Includes Quantum Startups

Methodology: Deep tech share 15%→71% of domestic tech investment (GPCA, 2017–2022). $138bn fund confirmed (ledger #149); ~$17.5bn now committed across three regional funds (new since the report). Newer context (not charted): China = 66% of Asia tech funding in 2024, down slightly from 69% in 2023; Chinese deep tech ~$6.2bn/241 rounds to Dec-2024, −26% in 2025; AI ~$10–11bn/yr since 2024 vs a 2021 peak of $23.3bn. fundUsdBn is USD bn. The 19.2% CAGR is excluded here and carried separately as a vendor forecast (ledger #144).

China tech investment composition, 2017–2022 (% of capital invested). Source: GPCA, 2023 Emerging Trends in Asia.

The payoff is visible. China’s Deep Tech market is projected to grow at a CAGR of 19.2% through 2034, outpacing the 15.6% projected for the United States and trailing only Australia & New Zealand’s 22% trajectory. The biotech sector dominated Deep Tech investments until recently, attracting roughly $22 billion in private capital, double the next largest vertical, computer hardware. But 2022 marked a pivot: biotech contracted sharply to $10 billion, while the EV, AV, and Automotive Technology segment surged from $7.9 billion to $11.1 billion, seizing the top position.

China’s deep tech bets shifted
private capital, 2022 (USD bn)
Biotech$10.0B
EV / AV / Automotive$11.1B

Biotech investment in China fell from ~$22bn to $10bn by 2022 while EV, autonomous and automotive rose from $7.9bn to $11.1bn, capital rotating toward strategic hardware. Bars show 2022; the table carries both years.

As originally publishedAs of September 2025Report p.102

The figure as the report published it, September 2025.

SourceGlobal Private Capital Association (GPCA), 2023 Emerging Trends in Asia

Methodology: GPCA 2023 (ledger #145/#146). biotech peak ≈22 (pre-2022) → 10 in 2022; EV/AV/auto 7.9 → 11.1, overtaking biotech. Four-year-old endpoint.

Private capital investment in top Deep Tech verticals in China, 2017–2022. Source: GPCA, 2023 Emerging Trends in Asia.

# Tangible outcomes of China’s Deep-Tech push

China has begun to harvest visible dividends. In January 2025, Beijing-based DeepSeek released its DeepSeek-R1 model, matching the best U.S. foundation models while training on far leaner compute budgets; analysts describe its open-weight successor as one of the strongest code-generation systems outside Silicon Valley. The same "thrift-at-scale" mindset underpins ManusAI, a Chinese agentic platform many observers rate above current state-of-the-art. A recent paper unveiled Zuchongzhi 3.0, a 105-qubit superconducting processor executing sampling tasks that stump classical supercomputers.

Hardware supremacy is most obvious on the road: Chinese brands account for about 60% of global EV sales, and in 2024 BYD shipped 4.27 million vehicles and booked USD 107 billion in revenue, outstripping Tesla’s 1.79 million deliveries and USD 97.7 billion top line. Furthermore, in March 2025 the General-Secretary of the Chinese Communist Party unveiled a US$138 billion public-private fund for quantum computing, advanced semiconductors, AI, and next-generation renewables. The quantum component alone is almost 30 times larger than the combined quantum programmes of the United States and European Union.

# Chinese engagement in LATAM

The United States and Europe still dominate Latin America’s investment landscape. In 2023 they supplied roughly 33% and 22% of incoming FDI, according to ECLAC; China registered a negligible 0.4%, a steep drop from the 3% it posted the year before. Even sources casting Beijing in a brighter light, such as the China OFDI Monitor, put its 2023 outlay at just USD 8.8 billion, about 10% of all FDI. Yet momentum is shifting: the European Union projects that by 2035 China will have become Latin America’s single largest trading partner.

Research by Melguizo and Myers shows the number of Chinese projects in Latin America grew by 33% from 2018–2023 versus 2013–2017, even as total value declined, more investments, smaller-scale projects, more focused on "new infrastructure." In 2022, 60% of China’s investments were in frontier sectors. Chinese investment shifted from canals, rails and energy infrastructure to Deep Tech, consistent with Beijing’s laser focus on economic upgrading. In 2022, China’s Ministry of Science and Technology explicitly committed to enhancing scientific cooperation with Latin America, emphasizing technology transfer.

China’s deep tech bets shifted
private capital, 2022 (USD bn)
Biotech$10.0B
EV / AV / Automotive$11.1B

Biotech investment in China fell from ~$22bn to $10bn by 2022 while EV, autonomous and automotive rose from $7.9bn to $11.1bn, capital rotating toward strategic hardware. Bars show 2022; the table carries both years.

As originally publishedAs of September 2025Report p.102

The figure as the report published it, September 2025.

SourceGlobal Private Capital Association (GPCA), 2023 Emerging Trends in Asia

Methodology: GPCA 2023 (ledger #145/#146). biotech peak ≈22 (pre-2022) → 10 in 2022; EV/AV/auto 7.9 → 11.1, overtaking biotech. Four-year-old endpoint.

China FDI in "New Infrastructure" industries, 2003–2022. Source: Melguizo & Myers, Ahead of the curve.

When we polled regional stakeholders about China’s footprint, most admitted they have yet to see sizeable cheques hit the ground. Interest is rising, particularly in biotech and ag-tech, but curiosity has not matured into transactions large enough to bend the market’s arc. Still, the real inflection arrives when states unleash large-scale public capital. In March 2025, China launched a US$138 billion sovereign vehicle, and only two months later rolled out a US$9 billion credit facility for Latin-American governments. The signal could not be clearer: China’s Deep Tech surge is inseparable from its bid to broaden its economic, and therefore geopolitical, ties across the hemisphere.

26 / 29 4 min

Middle Powers: A New Path for Deep Tech Advancement

p. 107

While China’s Deep Tech strategy illustrates the scale a global superpower can bring, LATAM countries face a dilemma: reliance on a single dominant partner risks overdependence and limits strategic flexibility. At the same time, partnerships with the United States are increasingly constrained by trade tensions, export controls, and shifting priorities.

In this context, LATAM can diversify its partnerships to access advanced technology, patient capital, and know-how without compromising autonomy. This is where partnering with "middle powers", technologically advanced, non-superpower nations such as Israel, South Korea, Singapore, Canada, Japan, the Gulf states and Australia, offers a strategic path forward. These countries occupy a sweet spot: technologically sophisticated and financially robust without the baggage of superpower status. They need partners, not dependants.

Currently, private-sector R&D funding in Latin America accounts for only 43% of total R&D expenditure, a sharp contrast to the 80% seen in a hub like Israel. LATAM faces three fundamental challenges that middle-power partnerships can address directly: capital, specifically the patient kind that allows Deep Tech to mature; knowledge transfer, connecting the region’s strong research talent to global innovation networks; and strategic autonomy, spreading risk across multiple partners. These partnerships succeed because they are built on mutual need rather than charity.

LATAM does not need to choose between the United States and China to build its technological future. By working with a diversified portfolio of middle powers, the region can access world-class innovation ecosystems, patient capital, and targeted knowledge transfer while maintaining strategic independence.

# Comparative case studies of middle-power strategies

Patient capital + infrastructure

United Arab Emirates

The UAE has taken the lead in LATAM. Over twelve months it signed Comprehensive Economic Partnership Agreements (CEPAs) with six LATAM countries, Colombia, Costa Rica, Chile, Mexico, Ecuador, and Brazil, committing more than US$100 billion and launching hyperscale data centers. Colombia offers the clearest example: following an April 2024 CEPA, MoUs quickly followed, including a Dubai Chambers office in Bogotá and three hyperscale data centers by G42. Costa Rica’s CEPA (February 2024) doubled non-oil trade; Chile is implementing tax incentives after its July 2024 accord; Mexico entered in June 2025 with a pact elevating semiconductors and AI.

Beyond digital infrastructure, in January 2025 Brazil signed a $2.5 billion MoU with the UAE focused on strategic minerals including copper and lithium, with explicit provisions for the transfer of cutting-edge technologies.,

Co-funded R&D

Canada

In 2020 Brazil’s innovation agency Embrapii and Canada’s National Research Council launched a co-funded R&D program under the Canadian International Innovation Program (CIIP). Starting April 2021, it finances joint Brazil-Canada projects in AI, IoT and advanced manufacturing, with eligible areas including agriculture, health and mining. It is one of the region’s clearest examples of a bilateral R&D partnership structured to support Deep Tech commercialization through government-backed co-investment.

Value-chain upgrading

Japan

In 2024 Japan and Brazil upgraded their strategic partnership to address energy-transition needs. Their Joint Action Plan pledges to strengthen mineral value chains, specifically battery-grade lithium refinement, and to share technical knowledge on recycling and processing, plus semiconductor policy experience. Japan has co-invested in LATAM lithium projects (Panasonic in Bolivia, Toyota in Argentina), and JICA invested $1 billion into the JICA-TADAC Fund managed by IDB Invest.

Bridge to rule-based frameworks

Singapore

Singapore acts as a gateway between East Asian technology and LATAM markets, having negotiated a Digital Economy Partnership Agreement (DEPA) with Chile and signed the Pacific Alliance–Singapore FTA., It has built one of the world’s most structured Deep Tech venture ecosystems, NUS GRIP, A*StartCentral, NTUitive, BLOCK71, SGInnovate, Enterprise Singapore, and Temasek-backed Xora Innovation, offering a template for joint funds, regional hubs, and exchange programs.

Industrial innovation + energy transition

South Korea

South Korea is supporting Chile in battery minerals and energy transition, including lithium processing and modernizing mining operations. Chilean officials have pursued MoUs on battery minerals and hydrogen; Chile and Korean partners collaborate on lithium joint ventures with state firms Codelco and ENAMI. A 2021 MoU covers green hydrogen, and Chile is adopting Industry 4.0 in its mines, autonomous trucks, AI-based ore-sorting, mirroring Korea’s smart manufacturing.

# Implementation frameworks

Each partnership highlights a different strategic lever: the UAE brings patient capital and infrastructure; South Korea offers industrial innovation tied to energy transition; Canada demonstrates co-funded R&D; Japan aligns technology transfer with value-chain upgrading; and Singapore provides a bridge to rule-based digital and trade frameworks. The case of Airbus can serve as a historical precedent for a consortium created for industrial and technological sovereignty, what began as a European response to American dominance in commercial aviation became one of the world’s most successful examples of multinational industrial cooperation.

Joint investment vehicles
Co-financing and blended-finance mechanisms are essential. Models like the Canada–Brazil CIIP illustrate successful bilateral co-investment; multilaterals such as the IDB Venture Lab or CAF could co-host innovation funds with Singaporean or UAE capital.
Technology transfer mechanisms
Formal R&D partnerships, secondments, and co-located labs accelerate capability building, Chile–Korea on hydrogen and smart mining, Canada–Brazil in nanotechnology, and Japan–Brazil on mineral processing and semiconductor policy.
Talent mobility and ecosystem integration
Exchange programs, fellowships, and targeted visas foster skill development, the Korea–Chile technical committee, Canada–Brazil joint research fellowships, and Japan’s JICA-backed training initiatives.

Success will require new forms of technological diplomacy, coordinated regional action, and the political will to think beyond traditional alliance structures. The convergence of global technological competition, shifting geopolitical alignments, and LATAM’s growing capabilities creates a unique window of opportunity.

27 / 29 2 min

Appropriation vs Autonomy: The Latin American Dilemma

p. 111

The new Chinese Digital Silk Road to LATAM could find greater space in the emptiness left by crumbling multilateralism and traditional alliances weakened by trade wars. The wave of export controls issued by the Trump administration is aimed at slowing China down on its path to Artificial General Intelligence. But will that be enough contingency?

First, DeepSeek has stunned techies and markets by releasing competitive AI models at a fraction of the cost of American rivals, showing that the Chinese model for top-down execution can be equally effective and more resourceful. Second, the battle for chips is crucial yet only in front of the war for technological supremacy. China started building its policies of coercion and appropriation well before its rivals, anticipating that value-based alliances would be replaced by interest-based ones.

It is possible that some allies will decide that, although they prefer the US, China is at least more predictable. That would be an insane position for these countries to be in. But it would be the almost inevitable result of Trump’s gangsterish approach to international relations.

Martin Wolf Financial Times

The new Cold War is much hotter on more fronts and with more players than the US and China wanting to take the stage. Take India, which now ranks in the top 5 in 45 of 64 technologies deemed critical by ASPI. Take Saudi Arabia and the UAE, spending hundreds of billions of petro-dollars to become technological and geopolitical hubs. This might change now, with geopolitics being more populous and driven by more selfish interests.

Regime type no longer appears to hinder a sense of shared interests. It is hard power only, and a return to the ancient principle that "the strong do what they can and the weak suffer what they must." In such a world, multilateral institutions such as NATO and the EU would be sidelined and the autonomy of smaller nations threatened.

Monica Duffy Toft Foreign Affairs

With less West and more Rest contending for tech dominance, Latin America will surely be a new battleground for innovation. Who appropriates what remains to be seen.

Our objective with the LADP is to present a holistic perspective on the state of Deep Tech and provide critical insights into the scaling challenges for the region. More importantly, we aim to present a practical series of recommendations on what we as a region must do to advance the investment landscape into the technologies that will shape our future. This process involves the meticulous development of robust intellectual property and a lengthy, strategic technology transfer from academia to the commercial sector, setting the indispensable foundation for groundbreaking, commercial innovation.

Successfully bridging this critical gap necessitates sustained investment and tailored support mechanisms, facilitating the arduous yet rewarding journey from scientific discovery to market-ready solutions. By systematically nurturing this intricate ecosystem, the region can unlock its full potential, transforming cutting-edge research into tangible economic growth and global leadership in Deep Tech.

Explore the 20 recommendations The practical playbook for closing the LATAM Discount.
28 / 29 1 min

Bibliography

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29 / 29 2 min

Contributors & Partners

p. 117

To shape our findings, we conducted interviews and roundtables with nearly 100 contributors who generously shared their time, insights, and perspectives. We extend our deepest thanks to them.

  • Alejandra Martínez Foundation Capital
  • Andrea Rochaix Argentine Association of Founders
  • Andy Pavia Glassnode
  • Annika Klump German-Argentine Chamber of Commerce
  • Ariel Muslera Borderless Capital
  • Beatriz Botero Sciences Po
  • Cameron Houser Actionworks
  • Camila Russo The Defiant
  • Carla Goglia Fundación Empretec
  • Christopher Storaker Arch Finance
  • Claudia Aparicio Olarte Moure & Alianza Deep Tech
  • Claudio Coconi Barceló Foundation
  • Cristian Hernández Zentynel
  • Cristóbal Díaz VSPT
  • David García Borderless Capital
  • Diana Silveira University of Palermo, Center for Startups
  • Diego Albúrez Max Planck Institute
  • Diego Fernández City of Buenos Aires, Secretary of Innovation
  • Elivan Álvarez Ripio Ventures
  • Erick Chacón Asafintech
  • Fausto Carbajal Miranda Partners
  • Florencia Gordillo ProtoTipas
  • Francis Sanchinelli U3Tech
  • Gabriel Bottos Vesper
  • Gabriel Pérez Pitanga
  • Geusseppe González Access Partnership
  • Idoia Ortiz de Artiñano Goñi Gobe
  • Ivone Padilla INCmty
  • Javier Bernal La Turbina Ventures
  • Javier Larragoiti Creative Food Labs
  • José Ignacio Torreblanca European Council on Foreign Relations
  • José Rodríguez Legalítika
  • Juan Soria SF500
  • Juan Vargas MenteX
  • Kun Peng Stanford Blockchain Accelerator
  • Kyle Becker JP Morgan, Former Researcher
  • Lisa Ocampo Emprear
  • Lucas Delgado Emerge Brasil
  • Lucas Toledo Universidad Nacional del Chaco Austral
  • Luis Barletta FEEDVAX
  • Manuel Leiva Facttic
  • Marilia Monteiro Nubank
  • Mark Veer Mantle
  • Markus Schreyer The Ganesha Labs
  • María Fernanda Andrés Aceleradora Litoral
  • Matías Peire GridX
  • Maxi Grande ADENEU
  • Nick Cohen International Strategy Forum
  • Nicolás Robinson Andrade OpenAI
  • Nicolás Salazar Cardona Inter-American Development Bank, GovTech
  • Orlando Ramírez Hello Tomorrow
  • Pablo Fernández Venturance
  • Pablo Cardozo Centro de Emprendedores UADE
  • Peter Bruck World Summit Awards
  • Ricardo Espinosa Tumo
  • Roberto Loehnert Zentynel
  • Rodrigo Vásquez Etherealize
  • Rogelio Marín Rómpela a la Mexicana
  • Said Saillant Societas Sapiens
  • Sandra Sinico ScaleupLatam
  • Sebastián Díaz Startup Chile, Former CEO
  • Sofía Quilici Forbes Magazine
  • Susana García Robles Capria VC
  • Tomaz Vicente Catalize Social
  • Toomas Ilves Former President of Estonia
  • Valentina Kraiselburd Asclepii
  • Vicente Pavani Startuplab.01
  • Zack Guzmán Yahoo/CNBC, Former Reporter
  • Óscar Mario Jiménez Academic Researcher
  • Franco Kraiselburd AVentures
  • Balint Pataki Center for Future Generations
  • Jean García Periche Center for Public Intelligence
  • Henry Woodfine Wood Mackenzie
  • Viviana Hermosilla CMPC Ventures
  • Nina Ploger Associate IPDES
  • José Brito Deep Tech Specialist
  • Carmen Contreras University of Oxford
  • Stephen Nordin International Strategy Forum
  • Clemente Gilardini Fusion Industry Association
  • Rafael Bottos Vesper Biotechnologies
  • Adilson Silva N7V
  • Sarah Morrill Activate
  • Danielle Moraes N7V
Meet the team & partners Authors, contributors, methodology and the organizations behind the LADP.